CdtR-mediated regulation of toxin production in Clostridium difficile
Clostridium difficile is the leading cause of hospital-associated diarrhoea in the developed world. Its pathogenicity is elicited by the production of up to three toxins: the monoglucosyltransferases TcdA and TcdB, and the ADP-ribosyltransferase, CDT. This thesis describes the generation and charact...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2019
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| Online Access: | https://eprints.nottingham.ac.uk/56279/ |