Identifying the metabolic 'Achilles heel' of adult and paediatric glioblastoma multiforme
Despite substantive efforts to characterise glioblastoma multiforme (GBM) at the molecular level, improvements to the overall survival of patients have yet to be seen within the clinic. Intratumour heterogeneity describes the co-existence of several subpopulations of GBM cells that are genetically d...
| Main Author: | Wood, James |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2019
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/56086/ |
Similar Items
Developing a sprayable drug delivery system for
the local delivery of nanoparticles in
glioblastoma multiforme
by: McCrorie, Phoebe
Published: (2021)
by: McCrorie, Phoebe
Published: (2021)
Molecular responses of U87-glioblastoma multiform cancer stem cells to HSV-G47Δ oncolytic virus in normoxia and hypoxia tumor microenvironments
by: Reza, Vazifehmand Rodposhtei
Published: (2021)
by: Reza, Vazifehmand Rodposhtei
Published: (2021)
MicroRNA analysis of the invasive margin of glioblastoma reveals drugable therapeutic targets in lipid metabolism pathways
by: Alfardus, Huda
Published: (2020)
by: Alfardus, Huda
Published: (2020)
Nanotherapeutics as a localised drug delivery system for the treatment of GBM
by: Vasey, Catherine E
Published: (2021)
by: Vasey, Catherine E
Published: (2021)
Apoferritin delivery of imidazotetrazine agents for targeted brain tumour therapy
by: Bouzinab, Kaouthar
Published: (2021)
by: Bouzinab, Kaouthar
Published: (2021)
The role of calcium activated and voltage gated potassium channel BK, in glioblastoma multiforme membrane potential.
by: Ratnasingham, Mathuscha
Published: (2024)
by: Ratnasingham, Mathuscha
Published: (2024)
Synthesis and Biological Evaluation of Novel Imidazotetrazines
by: Summers, Helen S
Published: (2019)
by: Summers, Helen S
Published: (2019)
Identifying metabolic biomarkers of physiological adaptation to change in physical activity and age
by: Alldritt, Isabelle
Published: (2023)
by: Alldritt, Isabelle
Published: (2023)
Enhanced dendritic cell immunotherapy to treat glioblastoma
by: Adhikaree, Jason
Published: (2019)
by: Adhikaree, Jason
Published: (2019)
Radiologic image-based statistical shape analysis of brain tumors
by: Bharath, Karthik, et al.
Published: (2018)
by: Bharath, Karthik, et al.
Published: (2018)
Development of Bioinformatic Methods to Determine Chemical Differences Between Nematode Species
by: Chauhan, Veeren
Published: (2022)
by: Chauhan, Veeren
Published: (2022)
Bioaccumulation and metabolic impact of environmental PFAS residue on wild-caught urban wetland tiger snakes (Notechis scutatus)
by: Lettoof, Damian, et al.
Published: (2023)
by: Lettoof, Damian, et al.
Published: (2023)
MicroRNA regulation of glycolytic metabolism in glioblastoma multiforme
by: Alfardus, Huda, et al.
Published: (2017)
by: Alfardus, Huda, et al.
Published: (2017)
New Approaches for Post-Surgical Treatment of Glioblastoma: Targeting GLI-Similar (GLIS) Genes with Stimuli-Responsive Polymer/RNA Complexes
by: Gumus, Nurcan
Published: (2024)
by: Gumus, Nurcan
Published: (2024)
Encapsulation of metal complex into apoferritin for drug delivery and prodrug activation
by: Cassioli, Maria Letizia
Published: (2023)
by: Cassioli, Maria Letizia
Published: (2023)
Regional profiling of abnormal protein expression & post translational modifications in glioblastoma
by: Kocon, Artur
Published: (2019)
by: Kocon, Artur
Published: (2019)
Surface Mass Spectrometry for in situ Metabolomic Analysis of Human Brain Tumours
by: He, Wenshi
Published: (2023)
by: He, Wenshi
Published: (2023)
Chlorotoxin as a Drug Delivery System to treat Glioblastoma
by: Fawzy, Ahmed Faadil
Published: (2021)
by: Fawzy, Ahmed Faadil
Published: (2021)
Development of an EGFR-targeted Drug Delivery System for Glioblastoma
by: Zhao, Zi-Ruo
Published: (2023)
by: Zhao, Zi-Ruo
Published: (2023)
Electrotherapy for the treatment of brain tumours
by: Branter, Joshua
Published: (2020)
by: Branter, Joshua
Published: (2020)
Surgical delivery of drug releasing
poly(lactic-co-glycolic acid)/poly(ethylene glycol)
paste with in vivo effects against glioblastoma
by: Smith, Stuart J., et al.
Published: (2014)
by: Smith, Stuart J., et al.
Published: (2014)
Surgical delivery of drug releasing poly(lactic-co-glycolic acid)/poly(ethylene glycol) paste with in vivo effects against glioblastoma
by: Smith, Stuart J., et al.
Published: (2014)
by: Smith, Stuart J., et al.
Published: (2014)
Recent advances in the therapeutic strategies of glioblastoma multiforme
by: Aldoghachi, Asraa Faris, et al.
Published: (2022)
by: Aldoghachi, Asraa Faris, et al.
Published: (2022)
Study of ischemia-reperfusion induced metabolite changes in porcine kidney model and their potential role in acute kidney injury
by: POLISETTY, RAVINDRA VARMA
Published: (2017)
by: POLISETTY, RAVINDRA VARMA
Published: (2017)
CD105 (Endoglin) exerts prognostic effects via its role
in the microvascular niche of paediatric high grade glioma
by: Smith, Stuart J., et al.
Published: (2012)
by: Smith, Stuart J., et al.
Published: (2012)
"Look at these new gadgets!": the achilles heel of technology-enhanced learning
by: Dobozy, Eva, et al.
Published: (2015)
by: Dobozy, Eva, et al.
Published: (2015)
Amirah's recurring injury may prove to be her achilles' heel
by: Singh, Aftar
Published: (2013)
by: Singh, Aftar
Published: (2013)
Redox Dichotomy in Cell Fate Decision: Evasive Mechanism or Achilles Heel?
by: Pervaiz, Shazib
Published: (2018)
by: Pervaiz, Shazib
Published: (2018)
Enhancing Supply Chain Resilience By Addressing The Achilles Heel Of Information Sharing
by: Tan, Hwee Chin
Published: (2019)
by: Tan, Hwee Chin
Published: (2019)
Studying relationship between increased 5-methylcytosine oxidation and expression of cancer stem cell markers in glioblastoma cell lines
by: Wijeyagumar, Vithusha
Published: (2018)
by: Wijeyagumar, Vithusha
Published: (2018)
Effects of growth promoters on sheep metabolism and growth
by: Al-Doski, Shaker
Published: (2015)
by: Al-Doski, Shaker
Published: (2015)
Credit risk: the Achilles’ heel of higher 3 capital under Basel norms
by: Rizvi, Noor, et al.
Published: (2020)
by: Rizvi, Noor, et al.
Published: (2020)
Glioblastoma multiforme identification from medical imaging using computer vision
by: Mohd. Azhari, Ed-Edily, et al.
Published: (2014)
by: Mohd. Azhari, Ed-Edily, et al.
Published: (2014)
Modified Swanson’s equation to detect the growth of glioblastomas multiforme (GBM) tumour
by: Mohd, Fashareena, et al.
Published: (2021)
by: Mohd, Fashareena, et al.
Published: (2021)
DEMARCATE: density-based magnetic resonance image clustering for assessing tumor heterogeneity in cancer
by: Saha, Abhijoy, et al.
Published: (2016)
by: Saha, Abhijoy, et al.
Published: (2016)
Overcoming therapeutic inertia as the achilles heel for improving suboptimal diabetes care: An integrative review
by: Chew, Boon-How, et al.
Published: (2023)
by: Chew, Boon-How, et al.
Published: (2023)
Development and application of multiple isotopes-assisted untargeted metabolomics in human health and disease
by: Evseev, Sergey
Published: (2019)
by: Evseev, Sergey
Published: (2019)
Epigenetic regulation of the secreted frizzled-related protein family in human glioblastoma multiforme
by: Schiefer, L., et al.
Published: (2014)
by: Schiefer, L., et al.
Published: (2014)
Development of lipid nanocapsules for antiangiogenic treatment of glioblastoma and evaluation of their potential for nose-to-brain drug delivery
by: Pourbaghi Masouleh, Milad
Published: (2019)
by: Pourbaghi Masouleh, Milad
Published: (2019)
Investigation of metabolic effects of polymer nanomedicines using advanced metabolomics methods
by: AbuHammad, Ala
Published: (2024)
by: AbuHammad, Ala
Published: (2024)
Similar Items
-
Developing a sprayable drug delivery system for
the local delivery of nanoparticles in
glioblastoma multiforme
by: McCrorie, Phoebe
Published: (2021) -
Molecular responses of U87-glioblastoma multiform cancer stem cells to HSV-G47Δ oncolytic virus in normoxia and hypoxia tumor microenvironments
by: Reza, Vazifehmand Rodposhtei
Published: (2021) -
MicroRNA analysis of the invasive margin of glioblastoma reveals drugable therapeutic targets in lipid metabolism pathways
by: Alfardus, Huda
Published: (2020) -
Nanotherapeutics as a localised drug delivery system for the treatment of GBM
by: Vasey, Catherine E
Published: (2021) -
Apoferritin delivery of imidazotetrazine agents for targeted brain tumour therapy
by: Bouzinab, Kaouthar
Published: (2021)