The role of SUMOylation in Liver X Receptor (LXR) transrepression of inflammatory responses

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The role of SUMOylation in Liver X Receptor (LXR) transrepression of inflammatory responses

Liver X Receptors (LXRs) are ligand-activated transcription factors that regulate genes involved in lipid metabolism, as well as those concerned with immune and inflammatory responses. SUMOylation of LXRs has been proposed to be central to the anti-inflammatory activity of LXRs in terms of transrepr...

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Bibliographic Details
Main Author:	Al-Momani, Razan
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2019
Subjects:	Ligand-activated transcription factors; Inflammatory responses; SUMO modification; Transactivation; Transrepression; Inflammatory signalling
Online Access:	https://eprints.nottingham.ac.uk/56057/

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