Small molecule-based fluorescent probes as tool compounds for chemokine receptors CXCR4 and ACKR3

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Small molecule-based fluorescent probes as tool compounds for chemokine receptors CXCR4 and ACKR3

Chemokine receptors CXCR4 and ACKR3 form, together with their shared ligand CXCL12, a highly intricate signalling axis that recently has emerged as a promising target for the treatment of cancer. To further the understanding of how these receptors function, and how they are involved in the various p...

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Bibliographic Details
Main Author:	Dekkers, Sebastian
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2019
Subjects:	Chemokine receptors; cancer treatment; fluorescent probes; ligands
Online Access:	https://eprints.nottingham.ac.uk/56054/

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