Low molecular weight nucleoside gelator: A novel approach for protein and peptide aggregation inhibition

QR Code

Low molecular weight nucleoside gelator: A novel approach for protein and peptide aggregation inhibition

Protein and peptide based therapeutics have become one of the most rapidly growing class of therapeutics that have potential to treat human disease. However, their inherent instability limits their application, which in turn minimises their therapeutic potential. Among all the physical and chemical...

Full description

Bibliographic Details
Main Author:	Johnson, Litty
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2019
Subjects:	gel nucleoside gelator protein aggregation inhibition protein therapeutics
Online Access:	https://eprints.nottingham.ac.uk/56035/

Similar Items

Low molecular mass nucleoside gelators for intra-tumoural drug delivery
by: Skilling, Kathryn J.
Published: (2016)

Nucleoside based self-assembling drugs for localized drug delivery
by: Skilling, Kathryn J., et al.
Published: (2018)

Macrocyclic gelators
by: Goh, Ching, et al.
Published: (2013)

Self-assembling tyrosine kinase inhibitors for localised targeted delivery
by: Al-Ameedee, Mohammed
Published: (2017)

Aggregation Prone Region analogues: synthetic excipients for protein formulation
by: Foralosso, Ruggero
Published: (2019)

Factors affecting Maillard induced gelation of protein-sugar systems
by: Azhar, Mat Easa
Published: (1996)

Study of consumer attitudes towards insect-based foods utilising Q method & the exploration of insect protein gels formulation.
by: Iliopoulou, Viktoria
Published: (2020)

Improving therapeutic protein formulation stability by optimising excipient properties
by: King, Toby
Published: (2025)

Impacts of Temperature-Induced Change of Formulation Buffers on the Stability of Proteins in Solution
by: Jeluk, Aimée
Published: (2025)

Structure and function of novel antifreeze peptides derived from Glaciozyma antarctica antifreeze protein-1
by: Said Amin Shah, Syed Hussinien Hielmie Shah
Published: (2013)

Synthesis and activity evaluation of short antifreeze peptides of type I shorthorn sculpin antifreeze protein
by: Suliman Warrad, Ahmad Omar Abdelazim
Published: (2013)

Examining the importance of survivin phosphorylation at Threonine 5 through its relationship with the kinase, TBK1, and the substrate, c-Src
by: Lishak, Jamie
Published: (2019)

Synthesis of nucleoside-boronic esters hydrophobic pro-drugs: a possible route to improve hydrophilic nucleoside drug loading into polymer nanoparticles
by: Abo-zeid, Yasmin, et al.
Published: (2018)

Amino acid functionalised calixarenes: crystal growth modifiers and low molecular weight gelators
by: Goh, Ching Yong
Published: (2012)

Structured vocabularies for proteins
by: Chang, Elizabeth, et al.
Published: (2005)

Advances in protein ontology project
by: Sidhu, Amandeep, et al.
Published: (2006)

Protein Structure-Based Design of Novel Semisynthetic Metallotrypsin
by: Misran, Azizah
Published: (2006)

Minimal processing of underutilised ingredients for food gel applications
by: Kremmyda, Alexandra
Published: (2024)

Sugar-derived compounds for gelation of various solvents and forming supramolecular dual-network materials for 3D printing applications
by: Dizon, Glenieliz
Published: (2022)

Periplasmic protein changes in response to over-expression of recombinant protein in escherichia coli
by: Heidary, Somayyeh
Published: (2013)

Both reversible self-association and structural changes underpin molecular viscoelasticity of mAb solutions
by: Sarangapani, Prasad S., et al.
Published: (2016)

Protein-Solvent Interaction of Thermostable Lipase for Biocatalysis in Organic Solvents
by: Tengku Abdul Hamid, Tengku Haziyamin
Published: (2009)

Bacterial back-talk: structural stability, unfolding and molecular interaction studies on Staphylococcal proteins
by: Zandomeneghi, Sara
Published: (2023)

Characterising the Structure and Functionality of Insect Proteins
by: Amor, D.R.
Published: (2024)

Structural investigation of alcohol oxidase from Meyerozyma guilliermondii and the use of its promoter for recombinant protein expression
by: Mahyon, Nur Iznida
Published: (2017)

Regulation of human heterochromatin protein 1 binding protein 3 (HP1BP3, also known as HP1BP74) in response to the DNA damage
by: Normatova, Makhliyo
Published: (2016)

Identification of differentially expressed proteins as biomarkers of acute myeloid leukaemia
by: Barantalab, Fatemeh
Published: (2014)

Self-assembling benzothiazole-based gelators: a mechanistic understanding of in vitro bioactivation and gelation
by: Citossi, Francesca, et al.
Published: (2018)

Exploring the surface of Trypanosoma brucei through protein sorting and recombinant expression
by: Miller, Thomas
Published: (2020)

Automated design of energy functions for protein structure prediction by means of genetic programming and improved structure similarity assessment
by: Widera, Paweł
Published: (2010)

Penggunaan Kaedah 2d-Page Untuk Kajian Pengekspresan Protein Semasa Embriogenesis Puntius gonionotus
by: Ahmat @ Amiruddin, Suhaida
Published: (2004)

Investigating a key autophagy protein-protein interaction and its modulation by phosphorylation and an ALS-related mutation
by: Brennan, Andrew
Published: (2019)

Ontological foundation for protein data models
by: Dillon, Tharam S., et al.
Published: (2005)

Molecular simulation of protein-ligand complexes
by: Guest, Ellen
Published: (2022)

Molecular level investigations of coiled-coil proteins
by: Johnson, Daniel
Published: (2006)

Identification, characterisation and functional analyses of novel beta-catenin associated protein, FLYWCH1
by: Muhammad, Belal Abdul-Rahman
Published: (2013)

Design, synthesis and activity studies of antifreeze peptide derived from type I shorthorn sculpin
by: Asmawi, Azren Aida
Published: (2015)

The Effects Of Varying Protein Levels On The Growth, Survival And Yield Of Penaeus Indicus Under Iranian Condition
by: Jahromi, Abdulhamid Yazdani
Published: (1995)

Rheological and textural characteristics of mango jam containing different gelling agents
by: Javanmard, Marjan
Published: (2011)

The fate of dosed copper to inhibit nitrification in chloraminated water distribution system
by: Zhan, Weixi
Published: (2007)