Modelling cell–matrix interactions in airway smooth muscle cells

QR Code

Modelling cell–matrix interactions in airway smooth muscle cells

Tissues, in both humans and animals, consist of cells embedded in a dynamic scaffold known as the extracellular matrix (ECM). Cells interact with the ECM through the process of cell–matrix adhesion, and these interactions, mediated by transmembrane proteins called integrins, are fundamental in regul...

Full description

Bibliographic Details
Main Author:	Irons, Linda
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2019
Subjects:	tissue extracellular matrix ECM cell–matrix adhesion asthma airway integrins
Online Access:	https://eprints.nottingham.ac.uk/55723/

Similar Items

MMP-1 activation contributes to airway smooth muscle growth and asthma severity
by: Naveed, Shams-un-nisa, et al.
Published: (2017)

Liver progenitor cell interactions with the extracellular matrix
by: Zhu, C., et al.
Published: (2012)

An in vitro and in silico study of altered airway smooth muscle structure and function in a remodelled asthmatic airway
by: Brown, Sarah
Published: (2023)

Matrix metalloproteinase-1 mediated extra-cellular matrix remodelling contributes to airway smooth muscle growth and asthma severity
by: Naveed, Shams-un-nisa
Published: (2018)

Dental stem cell delivery through new injectable matrices for spinal cord regeneration
by: Viswanath, Aiswarya
Published: (2018)

The differential effects of azithromycin on the airway epithelium in vitro and in vivo
by: Slater, Mariel, et al.
Published: (2016)

Decellularized bone extracellular matrix and human dental pulp stem cells as a construct for bone regeneration
by: Paduano, Francesco, et al.
Published: (2017)

Effects of Migrating Cell-Induced Matrix Reorganization on 3D Cancer Cell Migration
by: Sun, W., et al.
Published: (2014)

The role of histone arginine methylation in cytokine/chemokine gene expression in airway smooth muscle cells in asthma
by: Kaczmarek, Klaudia
Published: (2019)

Pharmacological ablation of the airway smooth muscle layer—Mathematical predictions of functional improvement in asthma
by: Donovan, G.M., et al.
Published: (2020)

Static and dynamic stress heterogeneity in a multiscale model of the asthmatic airway wall
by: Hiorns, Jonathan E., et al.
Published: (2016)

Macrophage phenotype in response to ECM bioscaffolds
by: Huleihel, Luai, et al.
Published: (2017)

Effect of cigarette smoke extract on inflammatory cytokine production and corticosteroid insensitivity in human airway smooth muscle cells
by: Alahmari, Mushabbab
Published: (2022)

A complex interplay between the extracellular matrix and the innate immune response to microbial pathogens
by: Tomlin, Hannah, et al.
Published: (2018)

Surface chemistry guidance in controllable neural stem cell differentiation to direct stem cell fate: future applications in building artificial neural networks
by: Dhowre, Hala Shakib
Published: (2018)

Aberrant DNA methylation and its regulation of gene expression in airway smooth muscle cells of individuals with asthma
by: Clifford, Rachel Louise
Published: (2023)

Parathyroid hormone-related peptide: a key factor in cell adhesion
by: Anderson, Jennifer Anne
Published: (2006)

Development of Crosslinked Bone Extracellular Matrix Hydrogels Using Naturally Derived Reagents
by: Jones, J.N.
Published: (2024)

In vitro, in silico and in vivo study challenges the impact of bronchial thermoplasty on acute airway smooth muscle mass loss
by: Chernyavsky, Igor L., et al.
Published: (2018)

Mathematical Models of Pro-remodelling Growth Factor Activation in Asthmatic Airways
by: Pybus, Hannah J.
Published: (2020)

Restoring mucosal barrier function and modifying macrophage phenotype with an extracellular matrix hydrogel: potential therapy for ulcerative colitis
by: Keane, Timothy J., et al.
Published: (2017)

Nephronectin and the genetics of lung function variability
by: Qian, Guoqing
Published: (2023)

Extracellular matrix hydrogels from decellularized tissues: structure and function
by: Saldin, Lindsey T., et al.
Published: (2017)

Customisable peptide hydrogels as user-defined biomimetic models of specific tissue microenvironments
by: Curd, Johnathan
Published: (2022)

Engineering ‘extracellular matrix factories’ to study how the extracellular microenvironment regulates gene expression
by: Tomlin, Hannah
Published: (2021)

ECM crosslinking enhances fibroblast growth and protects against matrix proteolysis in lung fibrosis
by: Philp, Christopher J., et al.
Published: (2017)

Development of biomimetic platforms to investigate the influence of the extra-cellular environment on immunological responses
by: Donaldson, Amy Rose
Published: (2017)

Developing platforms for tissue engineering of the airways
by: Ramis, Jopeth
Published: (2020)

Effects of 2,4,6-trihydroxy-3-geranyl acetophenone on growth factor-induced human bronchial smooth muscle cell proliferation in asthma
by: Yap, Hui Min
Published: (2018)

Airway remodeling blockade with an orally active geranyl acetophenone
by: Lee, Yu Zhao
Published: (2017)

Effect of loading history on airway smooth muscle cell-matrix adhesions
by: Irons, Linda, et al.
Published: (2018)

Regulation of ABCG2 through interactions with Alpha-1-Acid Glycoprotein and EMMPRIN
by: Likar, Sakura
Published: (2025)

Clonally expanded human airway smooth muscle cells exhibit morphological and functional heterogeneity
by: Singh, Shailendra R., et al.
Published: (2014)

Fabrication and Evaluation of Electrospun Silk Fibroin/Halloysite Nanotube Biomaterials for Soft Tissue Regeneration
by: Mohammadzadehmoghadam, Soheila, et al.
Published: (2022)

Molecular modelling of the interactions of complex carbohydrates with proteins
by: Gandhi, Neha Sureshchandra
Published: (2011)

Investigating the role of tumour-deposited extracellular matrix in medulloblastoma progression
by: Johnson, James E. C.
Published: (2023)

Expression and purification of the matrix protein of Nipah virus in baculovirus insect cell system
by: Dezfooli, Seyedehsara Masoomi, et al.
Published: (2016)

SOX9 predicts progression towards cirrhosis in patients while its loss protects against liver fibrosis
by: Athwal, Varinder S., et al.
Published: (2017)

Parametric solutions to Sylvester conjugate matrix equations
by: Wu, A., et al.
Published: (2011)

A prebiotic galactooligosaccharide mixture reduces severity of hyperpnoea-induced bronchoconstriction and markers of airway inflammation
by: Williams, Neil C., et al.
Published: (2016)