The role of survivin in autophagy
Survivin is a highly conserved protein with important roles in cell death and mitosis; deletion of the survivin gene is embryonically lethal. It is highly expressed in most cancers, making it a promising target for cancer therapy. Autophagy, an important homeostatic cellular recycling system, promot...
| Main Author: | Humphry, Nicola |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2018
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/55462/ |
Similar Items
The response of survivin to hypoxia and the functional roles of its subcellular pools.
by: Fezovich, Alexander
Published: (2023)
by: Fezovich, Alexander
Published: (2023)
The functional repertoire of survivin's tails
by: Wheatley, Sally P.
Published: (2015)
by: Wheatley, Sally P.
Published: (2015)
Mitotic activity of survivin is regulated by acetylation at K129
by: Aljaberi, Aysha M., et al.
Published: (2015)
by: Aljaberi, Aysha M., et al.
Published: (2015)
Investigating the relationship between Survivin and Tank-Binding Kinase 1 in cancer cells
by: Daly, Lauren
Published: (2021)
by: Daly, Lauren
Published: (2021)
Analysis of the functional repertoire of a mutant form of survivin, K129E, which has been linked to lung cancer
by: Aljaberi, Aysha M., et al.
Published: (2014)
by: Aljaberi, Aysha M., et al.
Published: (2014)
Identification of novel survivin interactors
by: Alhawsawi, Naif
Published: (2024)
by: Alhawsawi, Naif
Published: (2024)
Survivin and AURKA, key determinants of mitotic cell fate
by: Abdelkabir, Hana
Published: (2024)
by: Abdelkabir, Hana
Published: (2024)
The N-terminus of survivin is a mitochondrial-targeting sequence and Src regulator
by: Dunajova, Lucia, et al.
Published: (2016)
by: Dunajova, Lucia, et al.
Published: (2016)
Autophagy, citrullination and cancer
by: Durrant, LG
Published: (2016)
by: Durrant, LG
Published: (2016)
Cytokinesis is controlled by monomer-dimer switching of survivin
by: Zahim, Duaa
Published: (2024)
by: Zahim, Duaa
Published: (2024)
Metabolic stress and cancer: is autophagy the common denominator and a feasible target?
by: Giuliani, C., et al.
Published: (2014)
by: Giuliani, C., et al.
Published: (2014)
Investigating how survivin expression affects the cell death response induced by UV irradiation
by: Coe, Kirstie Danielle
Published: (2020)
by: Coe, Kirstie Danielle
Published: (2020)
Examining the importance of survivin phosphorylation at Threonine 5 through its relationship with the kinase, TBK1, and the substrate, c-Src
by: Lishak, Jamie
Published: (2019)
by: Lishak, Jamie
Published: (2019)
Defective recognition of LC3B by mutant SQSTM1/p62 implicates impairment of autophagy as a pathogenic mechanism in ALS-FTLD
by: Goode, Alice, et al.
Published: (2016)
by: Goode, Alice, et al.
Published: (2016)
Connecting MicroRNA and autophagy disturbances in Amyotrophic Lateral Sclerosis (ALS)
by: Foggin, Sophie
Published: (2022)
by: Foggin, Sophie
Published: (2022)
Doxorubicin-induced death in tumour cells and cardiomyocytes: is autophagy the key to improving future clinical outcomes?
by: Tacar, O., et al.
Published: (2013)
by: Tacar, O., et al.
Published: (2013)
Combinatorial application of tocotrienols and chemotherapeutic drugs enhances apoptosis and autophagy in colorectal cancer cells
by: Tham, Shiau Ying
Published: (2020)
by: Tham, Shiau Ying
Published: (2020)
Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacological modulation
by: Orfali, Nina, et al.
Published: (2015)
by: Orfali, Nina, et al.
Published: (2015)
Biophysical studies of ligand selectivity for the hATG8 family of autophagy proteins
by: Butler, Kevin
Published: (2021)
by: Butler, Kevin
Published: (2021)
Biphasic effects of autophagy on decompression bubble-induced endothelial injury
by: Wang, M., et al.
Published: (2019)
by: Wang, M., et al.
Published: (2019)
Investigating a key autophagy protein-protein interaction and its modulation by phosphorylation and an ALS-related mutation
by: Brennan, Andrew
Published: (2019)
by: Brennan, Andrew
Published: (2019)
Induction of autophagy by non-structural protein 6 in important animal and human coronaviruses
by: Daubrah-Scott, Tyler-Josh
Published: (2025)
by: Daubrah-Scott, Tyler-Josh
Published: (2025)
The role of SQSTM1/P62 in axonal development and degeneration in an ALS-FTLD context
by: Young, Matthew J.
Published: (2020)
by: Young, Matthew J.
Published: (2020)
The effects of a short-term (1-week) very low-calorie diet (850 calories) comparing low and normal protein content on cardiometabolic outcomes, glucose metabolism and autophagy
by: Burns, Lucy
Published: (2025)
by: Burns, Lucy
Published: (2025)
LIM kinase function and renal growth: potential role for LIM kinases in fetal programming of kidney development
by: Sparrow, Alexander J., et al.
Published: (2017)
by: Sparrow, Alexander J., et al.
Published: (2017)
High mobility group protein B1 is a predictor of poor survival in ovarian cancer
by: Machado, Lee R, et al.
Published: (2017)
by: Machado, Lee R, et al.
Published: (2017)
The role of mitochondrial survivin in phospholipid biosynthesis
by: Dunajova, Lucia
Published: (2016)
by: Dunajova, Lucia
Published: (2016)
Investigating the role of survivin in mitochondrial health
by: Townley, Amelia
Published: (2017)
by: Townley, Amelia
Published: (2017)
Contribution of Ref(2)p to regulation of Drosophila notum epithelial cell apico-basal polarity and phenotype
by: Shohayeb, Belal
Published: (2015)
by: Shohayeb, Belal
Published: (2015)
Acute depletion of diacylglycerol from the Cis-Golgi affects localised nuclear envelope morphology during mitosis
by: Chung, Gary Hong Chun, et al.
Published: (2018)
by: Chung, Gary Hong Chun, et al.
Published: (2018)
Characterisation of autophagosomes as a source of novel citrullinated antigens for use as a cancer vaccine
by: Heath, Bryony
Published: (2023)
by: Heath, Bryony
Published: (2023)
Citrullinated α-enolase is an effective target for anti-cancer immunity
by: Cook, Katherine, et al.
Published: (2018)
by: Cook, Katherine, et al.
Published: (2018)
N-term 2017: Proteostasis via the N-terminus
by: Dissmeyer, Nico, et al.
Published: (2017)
by: Dissmeyer, Nico, et al.
Published: (2017)
Nuclear survivin: cellular consequences and therapeutic implications
by: Wheatley, Sally P.
Published: (2011)
by: Wheatley, Sally P.
Published: (2011)
An Immunohistochemical, Study Of Survivin Expression In
Normal And In Transformed Cells
by: Alias, Iskandar Zulkarnain
Published: (2006)
by: Alias, Iskandar Zulkarnain
Published: (2006)
An Immunohistochemical Study Of Survivin Expression In
Normal And In Transformed Cells
by: Alias, Iskandar Zulkarnain
Published: (2006)
by: Alias, Iskandar Zulkarnain
Published: (2006)
Simultaneous knockdown of telomerase and survivin genes in HeLa cells
by: Chang, Loong Huat
Published: (2018)
by: Chang, Loong Huat
Published: (2018)
Cell-based assays for evaluation of autophagy in cancers
by: Pang, Siew Wai *, et al.
Published: (2019)
by: Pang, Siew Wai *, et al.
Published: (2019)
Autophagy and cancer: taking the ‘toxic’ out of cytotoxics
by: Giuliani, C., et al.
Published: (2013)
by: Giuliani, C., et al.
Published: (2013)
Expression of autophagy and mitophagy markers in breast cancer tissues
by: Mustafa, Mohd Fazirul, et al.
Published: (2021)
by: Mustafa, Mohd Fazirul, et al.
Published: (2021)
Similar Items
-
The response of survivin to hypoxia and the functional roles of its subcellular pools.
by: Fezovich, Alexander
Published: (2023) -
The functional repertoire of survivin's tails
by: Wheatley, Sally P.
Published: (2015) -
Mitotic activity of survivin is regulated by acetylation at K129
by: Aljaberi, Aysha M., et al.
Published: (2015) -
Investigating the relationship between Survivin and Tank-Binding Kinase 1 in cancer cells
by: Daly, Lauren
Published: (2021) -
Analysis of the functional repertoire of a mutant form of survivin, K129E, which has been linked to lung cancer
by: Aljaberi, Aysha M., et al.
Published: (2014)