Biased allosteric modulators at the metabotropic glutamate receptor 5

QR Code

Biased allosteric modulators at the metabotropic glutamate receptor 5

Bibliographic Details
Main Author:	Sengmany, Kathy
Format:	External Thesis
Language:	English
Published:	2018
Online Access:	https://eprints.nottingham.ac.uk/55447/

Similar Items

Biased allosteric modulators of metabotropic glutamate receptor 5
by: Sengmany, Kathy
Published: (2018)

Effects of the metabotropic glutamate receptor 5 positive allosteric modulator CDPPB on rats tested with the paired associates learning task in touchscreen-equipped operant conditioning chambers
by: Lins, Brittney, et al.
Published: (2016)

The impact of the metabotropic glutamate receptor and other gene family interaction networks on autism
by: Hadley, D., et al.
Published: (2014)

Biased allosteric modulation at the CaS receptor engendered by structurally diverse calcimimetics
by: Cook, A.E., et al.
Published: (2014)

Molecular determinants of allosteric modulation at the M1 muscarinic acetylcholine receptor
by: Abdul-Ridha, Alaa, et al.
Published: (2014)

Altered object exploration but not temporal order memory retrieval in an object recognition test following treatment of rats with the group II metabotropic glutamate receptor agonist LY379268
by: Lins, Brittney, et al.
Published: (2014)

Novel fused arylpyrimidinone based allosteric modulators of the M1 muscarinic acetylcholine receptor
by: Mistry, Shailesh N., et al.
Published: (2016)

Design, Synthesis, and Development of Novel Intracellular Allosteric Modulators of CXC Chemokine Receptor 1 and 2
by: Francis, Rhys
Published: (2024)

Universal sensors for identifying use-dependent intracellular allosteric modulators of G protein coupled receptors
by: Farmer, James
Published: (2024)

Medicinal Chemistry & Chemical Biology Approaches to Investigate Prospective Treatments for CNS Diseases: Dopamine D1 Receptor Positive Allosteric Modulators, Dopamine D2 Receptor Positive & Negative Allosteric Modulators, Dopamine D2 Receptor-Ligand Kinetics
by: Fyfe, Tim
Published: (2019)

Examining the mechanism of action of small-molecule negative allosteric modulators of the human chemokine receptor CXCR2
by: Nesheva, Desislava
Published: (2022)

Synthesis and pharmacological profiling of analogues of benzyl quinolone carboxylic acid (BQCA) as allosteric modulators of the M1 muscarinic receptor
by: Mistry, Shailesh N., et al.
Published: (2013)

Positive allosteric modulation of the muscarinic M1 receptor improves efficacy of antipsychotics in mouse glutamatergic deficit models of behavior
by: Choy, Kwok H.C., et al.
Published: (2016)

A thieno[2,3-d]pyrimidine scaffold is a novel negative allosteric modulator of the dopamine D2 receptor
by: Fyfe, Tim J., et al.
Published: (2018)

Discovery of a novel class of negative allosteric modulator of the dopamine D2 receptor through fragmentation of a bitopic ligand
by: Mistry, Shailesh N., et al.
Published: (2015)

4-Phenylpyridin-2-one derivatives: a novel class of positive allosteric modulator of the M1 muscarinic acetylcholine receptor
by: Mistry, Shailesh N., et al.
Published: (2015)

Mechanistic insights into allosteric structure-function relationships at the M1 muscarinic acetylcholine receptor
by: Abdul-Ridha, Alaa, et al.
Published: (2014)

Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor
by: Isogai, Shin, et al.
Published: (2016)

Allosteric interactions at adenosine A1 and A3 receptors: new insights into the role of small molecules and receptor dimerization
by: Hill, Stephen J., et al.
Published: (2014)

Investigations into β2-adrenoceptor pharmacology: kinetic analysis, mechanotransduction and allosteric modulation
by: Cullum, Sean A.
Published: (2024)

The modulation of NMDA and AMPA/kainate receptors by tocotrienol-rich fraction and A-tocopherol in glutamate-induced injury of primary astrocytes
by: Abedi, Zahra, et al.
Published: (2017)

Modulation of NMDA and AMPA/kainate receptors by tocotrienol-rich fraction and α-tocopherol in glutamate- induced injury of primary astrocytes
by: Abedi, Zahra
Published: (2017)

Assessment of the molecular mechanisms of action of novel 4-phenylpyridine-2-one and 6-phenylpyrimidin-4-one allosteric modulators at the M1 muscarinic acetylcholine receptors
by: van der Westhuizen, Emma T., et al.
Published: (2018)

Kinetic analysis of antagonist-occupied adenosine-A3 receptors within membrane microdomains of individual cells provides evidence of receptor dimerization and allosterism
by: Corriden, Ross, et al.
Published: (2014)

Vitamin E-mediated modulation of glutamate receptor expression in an oxidative stress model of neural cells derived from embryonic stem cell cultures
by: Jalil, Afifah Abd, et al.
Published: (2017)

Antinociceptive Effects of Cardamonin in Mice: Possible Involvement of TRPV1, Glutamate, and Opioid Receptors
by: Chung, Pui Ping, et al.
Published: (2018)

Antinociceptive effects of cardamonin in mice: Possible involvement of TRPV1, glutamate and opioid receptors
by: Chung, Pui Ping, et al.
Published: (2018)

Investigating the molecular basis of biased signalling at cannabinoid receptors
by: Dennis, Morgan Jane
Published: (2023)

The electrophysiology of ionotropic glutamate receptors expressed in human cell lines, HEK293 and TE671
by: Newman, Amy
Published: (2022)

Vitamin E in modulating cell viability and morphology of glutamate cell death in astrocytes
by: Khaza'ai, Huzwah, et al.
Published: (2016)

Studies on the biased signalling of some novel delta opioid receptor agonists
by: Asghar, Muhammad Junaid
Published: (2017)

Role of presynaptic glutamate receptors in Modulation of long term synaptic plasticity (LTP) in inhibitory synapes of visual pyramidal neuron after epilepsy: a whole cell patch clamp recording
by: Reza, Mohammed Faruque
Published: (2015)

Method for the biosynthesis of glutamic acid
by: Saari, Nazamid, et al.
Published: (2013)

Synthesis of novel esters of mefenamic acid with pronounced anti-nociceptive effects and a proposed activity on GABA, opioid and glutamate receptors
by: Ayoub, Rami, et al.
Published: (2021)

Novel complementation biosensors to investigate G protein-coupled receptor kinetics and signalling bias
by: Dijon, Nicola C
Published: (2022)

Modulation of C5A receptor in mammary gland tumour by EP54 and PMX205 peptides
by: Kosni, Nurneqman Nashreq
Published: (2015)

How Do Fatty Acids Cause Allosteric Binding of Drugs to Human Serum Albumin?
by: Chuang, Victor, et al.
Published: (2002)

Glutamate. Its applications in food and contribution to health.
by: Selamat, Jinap, et al.
Published: (2010)

Design, Synthesis, and Development of Novel Fluorescently Labelled Allosteric Probes for the Human Beta2-Adrenoceptor
by: Tuzer, Cemre
Published: (2023)

Hyperactive mariner transposons are created by mutations that disrupt allosterism and increase the rate of transposon end synapsis
by: Liu, Danxu, et al.
Published: (2014)