Hyperbranched polymers as non-viral vectors for gene delivery

QR Code

Hyperbranched polymers as non-viral vectors for gene delivery

The successful clinical translation of non-viral gene delivery systems has yet to be achieved due to the biological and technical obstacles to preparing a safe, potent and cost-effective vector. Hyperbranched polymers have emerged as promising candidates to address gene delivery barriers owing to th...

Full description

Bibliographic Details
Main Author:	Alazzo, Ali
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2018
Subjects:	Dendrimers; Polymers; Gene delivery
Online Access:	https://eprints.nottingham.ac.uk/55334/

Similar Items

Developing Mucous Penetrating Particles for Intestinal Gene Delivery using Non-viral GET Peptide System
by: Elnima, Alaa
Published: (2024)

Establishing and Utilising In Vitro Lung Models to Demonstrate Peptide Mediated Non-Viral Delivery
by: Smith, Lauren
Published: (2022)

Intraperitoneal delivery of nanoparticles for cancer gene therapy
by: Hallaj-Nezhadi, Somayeh, et al.
Published: (2013)

Non-covalent polymer and drug complexes as targeted delivery system for pulmonary delivery
by: Li, Huitong
Published: (2021)

Exploiting Multicomponent Polymerisations for Non-Viral Gene Delivery
by: O'Shaughnessy, Lewis
Published: (2025)

Synthesis and application of novel hyperbranched polymers
by: Goodwin, Sophie, R
Published: (2021)

Optimization for detecting the efficiency of viral-vectored gene delivery via intratumoural route in murine model
by: Mustafa, Nor Hidayah
Published: (2015)

Comparison of gene transfection and cytotoxicity mechanisms of linear poly(amidoamine) and branched poly(ethyleneimine) polyplexes
by: Almulathanon, Ammar A.Y., et al.
Published: (2018)

Tumour regression and improved gastrointestinal tolerability from controlled release of SN-38 from novel polyoxazoline-modified dendrimers
by: England, Richard M., et al.
Published: (2017)

Therapeutic intracellular delivery using magnetic fields, nanoparticle technology and enhanced cell penetrating peptides
by: Blokpoel Ferreras, Lia Andrea
Published: (2019)

Mixed anionic and cationic polyphosphazene complexes for effective gene delivery to glioblastoma in vitro and in vivo
by: Hsu, Wei-Hsin
Published: (2018)

Investigating Current Delivery Vehicles for Efficient and Targeted Delivery of Therapeutic RNA and Future Perspectives Part A - Investigating current delivery vehicles for efficient and targeted delivery of therapeutic RNA and future perspectives/ Part B - The development of novel polymeric nanoparticles as efficient non-viral RNA delivery vectors
by: Sachan, Isha
Published: (2023)

The characterisation and interactions of biomedical polymers
by: Black, Fiona E.
Published: (1999)

Structural variations in hyperbranched polymers prepared via thermal polycondensation of lysine and histidine and their effects on DNA delivery
by: Alazzo, Ali, et al.
Published: (2018)

Dry-powder formulations of non-covalent protein complexes with linear or miktoarm copolymers for pulmonary delivery
by: Nieto-Orellana, Alejandro, et al.
Published: (2018)

Non-viral gene delivery system
by: Mohamed, Farahidah, et al.
Published: (2015)

The structural functionalisation of poly(ß-amino esters) for drug delivery to bacterial biofilms
by: Kasza, Karolina Anna
Published: (2024)

Functionalising and Preserving Blood Platelets for Biologically Targeted Gene Therapies
by: Al athram, Nairouz
Published: (2025)

Synthesis, characterisation and applications of new polyesters for drug delivery
by: Kakde, Deepak
Published: (2016)

Current progress in non-viral vectors for cancer gene therapy
by: Ichwan, Solachuddin J. A.
Published: (2017)

Identification of novel ‘inks’ for 3D printing using high throughput screening: bioresorbable photocurable polymers for controlled drug delivery
by: Louzao, Iria, et al.
Published: (2018)

Evaluation of lipid liquid crystalline phase particles as drug delivery vectors
by: Xerri, Rachael
Published: (2021)

Preparation of hyperbranched polymers by controlled/living polymerisations
by: Zheng, Yu
Published: (2010)

Phytase Activity and Isolation of the Phytase Gene of Mitsuokella Jalaludinii
by: Phang, Chiun Yee
Published: (2008)

Computational modelling of polymer-based drug delivery systems
by: Mackenzie, R.C.
Published: (2015)

Modification of NanoCrystalline Cellulose (NCC) by Hyperbranched Polymer
by: Zianor Azrina, Z. A., et al.
Published: (2017)

New Approaches for Post-Surgical Treatment of Glioblastoma: Targeting GLI-Similar (GLIS) Genes with Stimuli-Responsive Polymer/RNA Complexes
by: Gumus, Nurcan
Published: (2024)

MODIFIED CELL PENETRATING PEPTIDES FOR EFFICIENT POLYMER NANO/MICROPARTICLE DELIVERY FOR BONE DIFFERENTIATION APPLICATIONS
by: Jalal, Aveen
Published: (2020)

Biomaterial-based local drug delivery to brain tumors
by: Rahman, Ruman
Published: (2014)

Preparation and characterisation of polymer microparticles with varying morphologies with application in drug delivery
by: Braz de Sousa, Ana Letícia
Published: (2020)

Diaminododecane-based cationic bolaamphiphile as a non-viral gene delivery carrier
by: Khan, M., et al.
Published: (2012)

Biocompatible hyperbranched polyglycerol modified ß-cyclodextrin derivatives for docetaxel delivery
by: Xu, Z., et al.
Published: (2017)

Development of a targeted drug delivery system for the treatment of hepatitis C virus infection
by: Baloch, Baby Kanwal
Published: (2012)

PEGylation of paclitaxel largely improves its safety and anti-tumor efficacy following pulmonary delivery in a mouse model of lung carcinoma
by: Luo, Tian, et al.
Published: (2016)

Development of functional micelles from biodegradable amphiphilic block copolymers for drug delivery and tumour therapy
by: Gulfam, Muhammad
Published: (2017)

Fabrication of non-viral gene delivery system of N.sativa/chitosan/PLGA nanoparticles
by: Mansor, Nur 'Izzati, et al.
Published: (2013)

Rational engineering of Apoferritin-based nanoparticles for drug delivery
by: Crowhurst, Samuel
Published: (2025)

OPTIMIZATION OF NOVEL POLYMERIC NANOPARTICLE FORMULATIONS FOR INHALED TARGETED THERAPY OF LUNG DISEASES
by: Elbahr, Ramy Said Hussenien Mohamed
Published: (2024)

Optimisation and Application of Biorenewable Polymers
by: Jacob, Philippa L.
Published: (2024)

Star-shaped poly(oligoethylene glycol) copolymer-based gels: thermo-responsive behaviour and bioapplicability for risedronate intranasal delivery
by: Soliman, Mahmoud E., et al.
Published: (2018)