Phosphorylation of PRH/HHEX by Protein Kinase CK2 Regulates Cell Proliferation and Cell Migration in Diverse Cell Types

QR Code

Phosphorylation of PRH/HHEX by Protein Kinase CK2 Regulates Cell Proliferation and Cell Migration in Diverse Cell Types

Disruption of the regulatory mechanisms that control cell proliferation and cell migration results in multiple disease states including cancer and leukemia. The Proline-Rich Homeodomain protein (PRH)/haematopoietically expressed homeobox protein (HHEX) is a transcription factor that controls cell pr...

Full description

Bibliographic Details
Main Authors:	Jayaraman, Padma-Sheela, Wadey, Kerry S., George, Sarah J., Gaston, Kevin
Format:	Book Section
Language:	English
Published:	InTechPublication 2018
Online Access:	https://eprints.nottingham.ac.uk/55051/

Similar Items

Identification of genes and pathways regulated by the PRH/HHEX transcription factor in endothelial and lymphatic cells
by: Dahhan, Rania
Published: (2024)

Investigating the effects of drug combinations and loss of the PRH/Hhex oncoprotein in CCA cells
by: Martin, Grace
Published: (2025)

The role of Proline-Rich Homeodomain protein PRH/HHEX in cholangiocarcinoma
by: Ghouth, Nahlah
Published: (2024)

Repressing the activity of protein kinase CK2 releases the brakes on mitochondria-mediated apoptosis in cancer cells
by: Hanif, I., et al.
Published: (2011)

Phosphorylation And Regulation Of Human Choline Kinase Beta By Protein Kinase A
by: Chang , Ching Ching
Published: (2015)

Phosphorylation And Regulation Of Human Choline Kinase Beta By Protein Kinase A
by: Chang , Ching Ching
Published: (2015)

LIM kinase and metanephric mesenchymal cell migration in the developing mouse kidney
by: Sparrow, Alexander
Published: (2016)

Analysis of phosphorylation sites of protein kinases in Cryptosporidium
by: Barudin, Mohd Aiman, et al.
Published: (2018)

The effect of budesonide and 5-azacytidine on the levels of methylation at the CpG islands of human choline kinase alpha (ckα) and beta (ckβ) promoter
by: Rahman, Muhammad Al Bunyamin Abdul
Published: (2017)

Effects of low glucose microenvironment on the proliferation, migration and senescence of meniscus-derived stem cells
by: Jiabei, Tong, et al.
Published: (2025)

NGAL is downregulated in oral squamous cell carcinoma and leads to increased survival, proliferation, migration and chemoresistance
by: Monisha, J., et al.
Published: (2018)

Differential mechanisms of angiotensin II and PDGF-BB on migration and proliferation of coronary artery smooth muscle cells
by: Allen, C.L., et al.
Published: (2008)

The Effect of Krill Oil and n-3 Polyunsaturated Fatty Acids on Human Osteosarcoma Cell Proliferation and Migration.
by: Xiao, S., et al.
Published: (2015)

Lipofection of single guide RNA targeting MMP8 decreases proliferation and migration in lung adenocarcinoma cells
by: Maradiaga, Oscar David Hernandez, et al.
Published: (2021)

Mesenchymal stem cells of human placenta and umbilical cord suppress T-cell proliferation at G0 phase of cell cycle
by: Vellasamy, Shalini, et al.
Published: (2013)

Redox regulation of cancer cell migration and invasion
by: Tochhawng, L., et al.
Published: (2013)

Defining the Anti-Cancer Activity of Tricarbonyl Rhenium Complexes: Induction of G2/M Cell Cycle Arrest and Blockade of Aurora-A Kinase Phosphorylation
by: Simpson, Peter, et al.
Published: (2017)

Effects of Migrating Cell-Induced Matrix Reorganization on 3D Cancer Cell Migration
by: Sun, W., et al.
Published: (2014)

Effects of protein kinase a phosphorylation on the biochemical properties and subcellular location of human choline kinase beta
by: Cun, See Too Wei
Published: (2016)

Effects Of Chrysin On The mRNA Expression Of Peroxisome Proliferator-Activated Receptor Alpha (PPARα) And Cyp Genes, Cell Cycle And Cell Migration In Colorectal Cancer Hct-116 Cells
by: Khor, Chin Yin
Published: (2020)

Factors regulating cortex cell file proliferation under low phosphorus stress in Arabidopsis thaliana roots
by: Janes, George
Published: (2018)

Cytotoxicity, proliferation and migration rate assessments of human dermal fibroblast adult cells using Zingiber zerumbet extract
by: Mazlyzam Abdul Latif,, et al.
Published: (2019)

The multiple facets of mesenchymal stem cells in modulating tumour cells’ proliferation and progression
by: Ramasamy, Rajesh, et al.
Published: (2019)

The Wnt regulator SFRP4 inhibits mesothelioma cell proliferation, migration, and antagonizes Wnt3a via its netrin-like domain
by: Perumal, Vanathi, et al.
Published: (2017)

Mesenchymal stem cells inhibit proliferation of lymphoid origin haematopoietic tumour cells by inducing cell cycle arrest
by: Sarmadi, Vahid Hosseinpour, et al.
Published: (2010)

Human bone marrow-derived Mesenchymal stem cells suppress T cell proliferation by inducing cell cycle arrest
by: Tong, Chih Kong, et al.
Published: (2008)

Long-term exposure to irinotecan reduces cell migration in glioma cells.
by: Al-Ghafari, Ayat B., et al.
Published: (2016)

Optimization of process conditions for high cell density proliferation of DF-1 cells in bioreactor
by: Mel, Maizirwan, et al.
Published: (2010)

Optimization of process conditions for high cell density proliferation of DF-1 cells in bioreactor
by: Mel, Maizirwan, et al.
Published: (2010)

Optimization of process conditions for high cell density proliferation of DF-1 cells in bioreactor
by: Mel, Maizirwan, et al.
Published: (2011)

Human mesenchymal stem cells impair the proliferation of monocytes through cell cycle interference
by: Maqbool, Maryam, et al.
Published: (2020)

Defect in serine 46 phosphorylation of p53 contributes to acquisition of p53 resistance in oral squamous cell carcinoma cells
by: Arief Ichwan, Solachuddin Jauhari, et al.
Published: (2006)

Inhibitory effect of mesenchymal stem cells on lymphocyte proliferation.
by: Gao, K., et al.
Published: (2008)

Zerumbone induces cytotoxicity and inhibits cell migration of human colon cancer cells
by: Tan, Min Jien, et al.
Published: (2020)

Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells.
by: Fernandez-Rojo, M., et al.
Published: (2018)

Directional capacity of human mesenchymal stem cells to support hematopoietic stem cell proliferation in vitro
by: Boroojerdi, Mohadese Hashem, et al.
Published: (2022)

A study of human choline kinase a (hCK-a) in patients with ischemic heart disease (ihd) and heal thy volunteers
by: Chia, Phee Phee
Published: (2008)

Phosphorylation of the PKG substrate, vasodilator-stimulated phosphoprotein (VASP), in human cultured prostatic stromal cells
by: Cook, Anna, et al.
Published: (2007)

Effect of iron chelators on proliferation and iron uptake in hepatoma cells
by: Kicic, Anthony, et al.
Published: (2001)

Evaluation of the "Cellscreen" system for proliferation studies on liver progenitor cells
by: Viebahn, C., et al.
Published: (2006)