Application of “smart” amine donors for rapid screening and scale-up of transaminase-mediated biotransformations

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Application of “smart” amine donors for rapid screening and scale-up of transaminase-mediated biotransformations

The “smart” amine donors o‐xylylenediamine and cadaverine were employed for the rapid screening of a large ketone library and subsequent preparative‐scale synthesis of selected compounds using a commercially available amine transaminase, ATA256. The methodology enables both screening and preparative...

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Bibliographic Details
Main Authors:	Gomm, Andrew, Grigoriou, Stylianos, Peel, Christopher, Ryan, James, Mujtaba, Nafees, Clarke, Thomas, Kulcinskaja, Evelina, O'Reilly, Elaine
Format:	Article
Language:	English
Published:	Wiley 2018
Online Access:	https://eprints.nottingham.ac.uk/53766/

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