Design and synthesis of small molecule inhibitors of coagulation FXIIa

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Design and synthesis of small molecule inhibitors of coagulation FXIIa

Blood coagulation factors, factor XII (FXII), plasma kallikrein (PK), factor XI (FXI), and high-molecular-weight kininogen (HMWK), are four proteins that are involved in the plasma contact activation system (CAS) and kallikrein-kinin system (KKS). FXII is the initiation point of the intrinsic pathwa...

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Bibliographic Details
Main Author:	Chen, Xi
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2018
Subjects:	Blood coagulation factors; Inhibitors; Haemostasis
Online Access:	https://eprints.nottingham.ac.uk/53481/

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