Mixed anionic and cationic polyphosphazene complexes for effective gene delivery to glioblastoma in vitro and in vivo

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Mixed anionic and cationic polyphosphazene complexes for effective gene delivery to glioblastoma in vitro and in vivo

Gene delivery vectors that are safe, efficient and affordable could significantly enhance the prospects for genetic-based therapies. Here we describe an approach to such vectors, using new variants of polyphosphazene materials and describe the synthesis of a series of degradable polyphosphazenes wit...

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Bibliographic Details
Main Author:	Hsu, Wei-Hsin
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2018
Subjects:	Poly(phosphazene)s click chemistry polymeric gene delivery siRNA delivery glioblastoma tumor initiating cells
Online Access:	https://eprints.nottingham.ac.uk/53452/

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