Reprogramming to cancer induced pluripotent stem cells elucidates the contribution of genetic and epigenetic alterations to breast carcinogenesis

QR Code

Reprogramming to cancer induced pluripotent stem cells elucidates the contribution of genetic and epigenetic alterations to breast carcinogenesis

The induced pluripotent stem cells (iPSCs) technology has revolutionized disease modelling by enabling the generation of patient-specific pluripotent stem cells for the study of complex disorders such as cancer. Somatic cell reprogramming through iPSCs induces global epigenetic reconfiguration of th...

Full description

Bibliographic Details
Main Author:	Leong, Yeh Chwan
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2018
Online Access:	https://eprints.nottingham.ac.uk/53330/

Similar Items

Advancements in reprogramming strategies for the generation of induced pluripotent stem cells.
by: Lai, Mei I., et al.
Published: (2011)

Ovine induced pluripotent stem cells are resistant to reprogramming after nuclear transfer
by: German, Sergio D., et al.
Published: (2015)

Induced pluripotent stem cells: reprogramming platforms and applications in cell replacement therapy
by: Al Abbar, Akram, et al.
Published: (2020)

Early epigenetic reprogramming in fertilized, cloned, and parthenogenetic embryos
by: Sepulveda-Rincon, Lessly P., et al.
Published: (2016)

Dynamics of epigenetic control on transgene expression mediated by lentivirus in mouse pluripotent stem cells
by: Alhaji, Suleiman Yusuf
Published: (2018)

Gene regulatory network and epigenetic reprogramming of pig primordial germ cells
by: Zhang, Haixin
Published: (2016)

Epigenetic reprogramming converts human Wharton's jelly mesenchymal stem cells into functional cardiomyocytes by differential regulation of Wnt mediators
by: Bhuvanalakshmi, G., et al.
Published: (2017)

Evaluation of minicircle-induced pluripotent stem cell
by: Daneshvar, Nasibeh
Published: (2014)

Esophageal stem cells and genetics/epigenetics in esophageal cancer
by: Croagh, D., et al.
Published: (2014)

Induced pluripotent stem cells: history, properties and potential applications
by: Nordin, Norshariza, et al.
Published: (2011)

Developing a model system to investigate the epigenetic mechanisms underlying pluripotency in human cells
by: Matsa, Elena
Published: (2010)

The establishment of in vitro human induced pluripotent stem cell-derived neurons
by: Izyan Mohd Idris,, et al.
Published: (2023)

Hematopoietic cell differentiation from embryonic and induced pluripotent stem cells
by: Lim, Wai Feng, et al.
Published: (2013)

Elucidating the role of the SATB1 gene in breast cancer carcinogenesis in the presence or absence of tocotrienol-rich fraction : evidence from a syngeneic mouse model of breast cancer
by: Sitti Rahma Abdul Hafid,, et al.
Published: (2021)

Using human induced pluripotent stem cells to study the in vitro phenotype of the cardiac channelopathies
by: Duncan, Gary
Published: (2017)

Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells
by: Sampaziotis, Fotios, et al.
Published: (2017)

Evaluating human induced pluripotent stem cell-derived cardiomyocytes for commercial drug testing
by: Katili, Puspita Anggraini
Published: (2020)

Development and Characterisation of AML-M5-Derived Induced Pluripotent Stem Cells (IPSCS)
by: Chiew, Men Yee
Published: (2015)

A plethora of human pluripotent stem cells
by: Liyang, Gao, et al.
Published: (2013)

The genetic and epigenetic landscapes of the epithelium in asthma
by: Moheimani, F., et al.
Published: (2016)

Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation
by: Sampaziotis, Fotios, et al.
Published: (2015)

Preparation of induced pluripotent stem cells on dishes grafted on oligopeptide under feeder-free conditions
by: Higuchi, Akon, et al.
Published: (2014)

Recent developments in β-cell differentiation of pluripotent stem cells induced by small and large molecules
by: Kumar, S. Suresh, et al.
Published: (2014)

Generation and Characterisation of Induced Pluripotent Stem Cells Derived from Human Hair Follicle Keratinocytes
by: Lim, Sheng Jye
Published: (2015)

Elucidation Of DNA Damage Response Pathways And Functional Efficiency Of DNA Repair Genes Associated With Reprogrammed Osteosarcoma Cell Lines
by: Choong, Pei Feng
Published: (2018)

Liver carcinogenesis
by: Tirnitz-Parker, Janina, et al.
Published: (2009)

Camptothecin encapsulated in β-Cyclodextrin-EDTA-Fe3O4 nanoparticles induce metabolic reprogramming repair in HT29 cancer cells through epigenetic modulation: a bioinformatics approach
by: Farhana, Aisha, et al.
Published: (2021)

Establishment of the human cardiac models using gene editing and reprogramming in Human Pluripotent Stem Cells to understand the putative functions of the G-protein coupled receptor kinase 5 polymorphism (GRK5-L41)
by: Hoang, Minh Duc
Published: (2017)

Role of epigenetic modulation in cancer stem cell fate
by: Deshmukh, A., et al.
Published: (2017)

Automation and scale-up of human induced pluripotent stem cell models of cardiovascular disease for drug screening
by: Crutchley, James E.B.
Published: (2016)

Lack of methylation on transgene leads to high level and persistent transgene expression in induced pluripotent stem cells
by: Alhaji, Suleiman Yusuf, et al.
Published: (2020)

The design of a thermoresponsive surface for the continuous culture of human pluripotent stem cells
by: Sung, Tzu Cheng, et al.
Published: (2019)

Iron and Hepatic Carcinogenesis
by: Tirnitz-Parker, Janina, et al.
Published: (2013)

Linking molecular targets to hypertrophic cardiomyopathy using genome-edited human induced pluripotent stem cell cardiomyocytes
by: Bodbin, S.E.
Published: (2022)

Generation of induced pluripotent stem cells by a polycistronic lentiviral vector in feeder- and serum- free defined culture
by: Al Abbar, Akram Faisal Mahmaud, et al.
Published: (2018)

Generation of mouse induced pluripotent stem cells using polycistronic lentiviral vector in feeder - and serum-free culture
by: Mahmaud, Akram Faisal
Published: (2015)

Defining and manipulating the epigenetic stability of human embryonic stem cells
by: Kim, Kee-Pyo
Published: (2009)

Genetic and epigenetic regulation of phosphoinositide 3-kinase isoforms
by: Fyffe, C., et al.
Published: (2013)

Identification of oocyte reprogramming factors and mechanisms
by: Mola, Choulia
Published: (2017)

Current techniques in reprogramming cell potency
by: Romli, Firdaus, et al.
Published: (2013)