Taking a broader view of things: towards a transdisciplinary approach to cancer

Cancer is widely considered an abnormality that emerges from within the body and which must be destroyed and defeated. But we still do not know precisely how and why cancer starts, and while a ‘magic bullet’ cure has failed to materialise, those adopting a more pragmatic stance are increasingly argu...

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Main Authors: Rauch, Cyril, Blott, Sarah, Stewart, Simon
Format: Article
Published: Sapienza, Universita di Roma 2017
Subjects:
Online Access:https://eprints.nottingham.ac.uk/53090/
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author Rauch, Cyril
Blott, Sarah
Stewart, Simon
author_facet Rauch, Cyril
Blott, Sarah
Stewart, Simon
author_sort Rauch, Cyril
building Nottingham Research Data Repository
collection Online Access
description Cancer is widely considered an abnormality that emerges from within the body and which must be destroyed and defeated. But we still do not know precisely how and why cancer starts, and while a ‘magic bullet’ cure has failed to materialise, those adopting a more pragmatic stance are increasingly arguing that if we cannot eradicate all cancer cells, we should look instead towards a ‘stalemate’ and find ways of managing cancer as a chronic disease. This article seeks to extend the reach of research in this field by taking a broader view and working towards a transdisciplinary approach in order to better understand cancer. First, we draw attention to obstacles that hinder progress in formulating new perspectives on cancer. Second, we ask why the genocentric approach to cancer remains dominant. One explanation is the legacy of Cartesian thinking. Third, we consider new ways of conceptualizing cancer so that it is not only a scientific object but also an object of life that has a framed existence within the body as part of a wider process of biological evolution. We draw on two key examples which highlight the importance of adopting a transdisciplinary approach: multi-drug resistance and cancer genomics.
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spelling nottingham-530902020-05-04T19:25:07Z https://eprints.nottingham.ac.uk/53090/ Taking a broader view of things: towards a transdisciplinary approach to cancer Rauch, Cyril Blott, Sarah Stewart, Simon Cancer is widely considered an abnormality that emerges from within the body and which must be destroyed and defeated. But we still do not know precisely how and why cancer starts, and while a ‘magic bullet’ cure has failed to materialise, those adopting a more pragmatic stance are increasingly arguing that if we cannot eradicate all cancer cells, we should look instead towards a ‘stalemate’ and find ways of managing cancer as a chronic disease. This article seeks to extend the reach of research in this field by taking a broader view and working towards a transdisciplinary approach in order to better understand cancer. First, we draw attention to obstacles that hinder progress in formulating new perspectives on cancer. Second, we ask why the genocentric approach to cancer remains dominant. One explanation is the legacy of Cartesian thinking. Third, we consider new ways of conceptualizing cancer so that it is not only a scientific object but also an object of life that has a framed existence within the body as part of a wider process of biological evolution. We draw on two key examples which highlight the importance of adopting a transdisciplinary approach: multi-drug resistance and cancer genomics. Sapienza, Universita di Roma 2017-12-31 Article PeerReviewed Rauch, Cyril, Blott, Sarah and Stewart, Simon (2017) Taking a broader view of things: towards a transdisciplinary approach to cancer. Organisms. Journal of Biological Sciences, 1 (2). pp. 49-59. ISSN 2532-5876 cancer transdisciplinary approach sociology philosophy science multi-drug resistance cancer genomics https://ojs.uniroma1.it/index.php/Organisms/article/view/13976 doi:10.13133/2532-5876_2.10 doi:10.13133/2532-5876_2.10
spellingShingle cancer
transdisciplinary approach
sociology
philosophy
science
multi-drug resistance
cancer genomics
Rauch, Cyril
Blott, Sarah
Stewart, Simon
Taking a broader view of things: towards a transdisciplinary approach to cancer
title Taking a broader view of things: towards a transdisciplinary approach to cancer
title_full Taking a broader view of things: towards a transdisciplinary approach to cancer
title_fullStr Taking a broader view of things: towards a transdisciplinary approach to cancer
title_full_unstemmed Taking a broader view of things: towards a transdisciplinary approach to cancer
title_short Taking a broader view of things: towards a transdisciplinary approach to cancer
title_sort taking a broader view of things: towards a transdisciplinary approach to cancer
topic cancer
transdisciplinary approach
sociology
philosophy
science
multi-drug resistance
cancer genomics
url https://eprints.nottingham.ac.uk/53090/
https://eprints.nottingham.ac.uk/53090/
https://eprints.nottingham.ac.uk/53090/