Cognitive neuroscience using wearable magnetometer arrays: non-invasive assessment of language function
Recent work has demonstrated that Optically Pumped Magnetometers (OPMs) can be utilised to create a wearable Magnetoencephalography (MEG) system that is motion robust. In this study, we use this system to map eloquent cortex using a clinically validated language lateralisation paradigm (covert verb...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
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Elsevier
2018
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| Online Access: | https://eprints.nottingham.ac.uk/53029/ |
| _version_ | 1848798862605549568 |
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| author | Tierney, Tim M. Holmes, Niall Meyer, Sofie S. Boto, Elena Roberts, Gillian Leggett, James Buck, Sarah Duque-Muñoz, Leonardo Litvak, Vladimir Bestmann, Sven Baldeweg, Torsten Bowtell, Richard W. Brookes, Matthew J. Barnes, Gareth R. |
| author_facet | Tierney, Tim M. Holmes, Niall Meyer, Sofie S. Boto, Elena Roberts, Gillian Leggett, James Buck, Sarah Duque-Muñoz, Leonardo Litvak, Vladimir Bestmann, Sven Baldeweg, Torsten Bowtell, Richard W. Brookes, Matthew J. Barnes, Gareth R. |
| author_sort | Tierney, Tim M. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Recent work has demonstrated that Optically Pumped Magnetometers (OPMs) can be utilised to create a wearable Magnetoencephalography (MEG) system that is motion robust. In this study, we use this system to map eloquent cortex using a clinically validated language lateralisation paradigm (covert verb generation: 120 trials, ~10 minutes total duration) in healthy adults (n=3). We show that it is possible to lateralise and localise language function on a case by case basis using this system. Specifically, we show that at a sensor and source level we can reliably detect a lateralising beta band (15-30Hz) desynchronization in all subjects. This is the first demonstration of studying human cognition with OPMs and not only highlights this technology’s utility as tool for (developmental) cognitive neuroscience but also its potential to contribute to surgical planning via mapping of eloquent cortex, especially in young children. |
| first_indexed | 2025-11-14T20:26:31Z |
| format | Article |
| id | nottingham-53029 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T20:26:31Z |
| publishDate | 2018 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-530292020-05-04T19:46:07Z https://eprints.nottingham.ac.uk/53029/ Cognitive neuroscience using wearable magnetometer arrays: non-invasive assessment of language function Tierney, Tim M. Holmes, Niall Meyer, Sofie S. Boto, Elena Roberts, Gillian Leggett, James Buck, Sarah Duque-Muñoz, Leonardo Litvak, Vladimir Bestmann, Sven Baldeweg, Torsten Bowtell, Richard W. Brookes, Matthew J. Barnes, Gareth R. Recent work has demonstrated that Optically Pumped Magnetometers (OPMs) can be utilised to create a wearable Magnetoencephalography (MEG) system that is motion robust. In this study, we use this system to map eloquent cortex using a clinically validated language lateralisation paradigm (covert verb generation: 120 trials, ~10 minutes total duration) in healthy adults (n=3). We show that it is possible to lateralise and localise language function on a case by case basis using this system. Specifically, we show that at a sensor and source level we can reliably detect a lateralising beta band (15-30Hz) desynchronization in all subjects. This is the first demonstration of studying human cognition with OPMs and not only highlights this technology’s utility as tool for (developmental) cognitive neuroscience but also its potential to contribute to surgical planning via mapping of eloquent cortex, especially in young children. Elsevier 2018-07-13 Article PeerReviewed Tierney, Tim M., Holmes, Niall, Meyer, Sofie S., Boto, Elena, Roberts, Gillian, Leggett, James, Buck, Sarah, Duque-Muñoz, Leonardo, Litvak, Vladimir, Bestmann, Sven, Baldeweg, Torsten, Bowtell, Richard W., Brookes, Matthew J. and Barnes, Gareth R. (2018) Cognitive neuroscience using wearable magnetometer arrays: non-invasive assessment of language function. NeuroImage . ISSN 1095-9572 (In Press) Optically pumped magnetometers; Language; MEG |
| spellingShingle | Optically pumped magnetometers; Language; MEG Tierney, Tim M. Holmes, Niall Meyer, Sofie S. Boto, Elena Roberts, Gillian Leggett, James Buck, Sarah Duque-Muñoz, Leonardo Litvak, Vladimir Bestmann, Sven Baldeweg, Torsten Bowtell, Richard W. Brookes, Matthew J. Barnes, Gareth R. Cognitive neuroscience using wearable magnetometer arrays: non-invasive assessment of language function |
| title | Cognitive neuroscience using wearable magnetometer arrays: non-invasive assessment of language function |
| title_full | Cognitive neuroscience using wearable magnetometer arrays: non-invasive assessment of language function |
| title_fullStr | Cognitive neuroscience using wearable magnetometer arrays: non-invasive assessment of language function |
| title_full_unstemmed | Cognitive neuroscience using wearable magnetometer arrays: non-invasive assessment of language function |
| title_short | Cognitive neuroscience using wearable magnetometer arrays: non-invasive assessment of language function |
| title_sort | cognitive neuroscience using wearable magnetometer arrays: non-invasive assessment of language function |
| topic | Optically pumped magnetometers; Language; MEG |
| url | https://eprints.nottingham.ac.uk/53029/ |