Risks and benefits of direct oral anticoagulants versus warfarin in a real world setting: cohort study in primary care

QR Code

Risks and benefits of direct oral anticoagulants versus warfarin in a real world setting: cohort study in primary care

Objective: To investigate the associations between direct oral anticoagulants (DOACs) and risks of bleeding, ischaemic stroke, venous thromboembolism, and all cause mortality compared with warfarin. Design: Prospective open cohort study. Setting: UK general practices contributing to QResearch...

Full description

Bibliographic Details
Main Authors:	Vinogradova, Yana, Coupland, Carol, Hill, Trevor, Hippisley-Cox, Julia
Format:	Article
Published:	BMJ Publishing Group 2018
Subjects:	Direct oral anticoagulants; DOACS; Warfarin; Primary Care; Bleeding; risks of bleeding; Ischaemic stroke; Venous thromboembolism; All cause mortality
Online Access:	https://eprints.nottingham.ac.uk/52928/

Similar Items

Predicting risk of upper gastrointestinal bleed and intracranial bleed with anticoagulants: cohort study to derive and validate the QBleed scores
by: Hippisley-Cox, Julia, et al.
Published: (2014)

Protocol to assess the effectiveness and safety of novel oral anticoagulants (NOAC) vs warfarin in real world settings: cohort study in primary care
by: Hippisley-Cox, Julia, et al.
Published: (2016)

Protocol to assess risk of venous thromboembolism associated with use of hormone replacement therapy in real world settings: two nested case-control studies in primary care
by: Vinogradova, Yana, et al.
Published: (2018)

Antidepressant use and risk of adverse outcomes in people aged 20–64 years: cohort study using a primary care database
by: Coupland, Carol, et al.
Published: (2018)

Compression stockings and the prevention of symptomatic venous thromboembolism: data from the Tinzaparin in Acute Ischaemic Stroke Trial
by: Sprigg, Nikola, et al.
Published: (2005)

Diabetes treatments and risk of heart failure, cardiovascular disease and all-cause mortality: cohort study in primary care
by: Hippisley-Cox, Julia, et al.
Published: (2016)

Myocardial infarction after intravitreal vascular endothelial growth factor inhibitors: a whole population study
by: Kemp, A., et al.
Published: (2013)

Baseline characteristics of the 3,096 patients recruited into the 'Triple Antiplatelets for Reducing Dependency after Ischaemic Stroke' (TARDIS) trial
by: Bath, Philip M.W., et al.
Published: (2017)

Comorbidities affect risk of nonvariceal upper gastrointestinal bleeding
by: Crooks, Colin John, et al.
Published: (2013)

Universal definition of perioperative bleeding in adult cardiac surgery
by: Dyke, C., et al.
Published: (2014)

Clinical utility of remote platelet function measurement using P-selectin: assessment of aspirin, clopidogrel, and prasugrel and bleeding disorders
by: Bath, Philip M., et al.
Published: (2018)

Clinical utility of remote platelet function measurement using P-selectin: assessment of aspirin, clopidogrel and prasugrel, and bleeding disorders
by: Bath, Philip M.W., et al.
Published: (2018)

Incidence of venous thromboembolism following colorectal surgery
by: Lewis-Lloyd, Christopher A.
Published: (2023)

A regional citrate anticoagulation protocol for pre-dilutional CVVHDf: The 'Modified Alabama Protocol'
by: Davies, Hugh, et al.
Published: (2008)

Detailed structure of the venous drainage of the brain: relevance to accidental and non-accidental traumatic head injuries
by: Nakagawa, Seneka
Published: (2014)

Venous thromboembolism in children with cancer – a population-based cohort study
by: Walker, Alex J., et al.
Published: (2014)

Amphetamine increases blood pressure and heart rate but has no effect on motor recovery or cerebral haemodynamics in ischaemic stroke: a randomized controlled trial (ISRCTN 36285333)
by: Sprigg, Nikola, et al.
Published: (2007)

There will be blood: autohaemorrhage behaviour as part of the defence repertoire of an insect
by: Bateman, Bill, et al.
Published: (2009)

Variation in the risk of venous thromboembolism in people with colorectal cancer: a population-based cohort study from England
by: Walker, A.J., et al.
Published: (2014)

Stroke severity, early recovery and outcome are each related with clinical classification of stroke: data from the 'Tinzaparin in Acute Ischaemic Stroke Trial (TAIST)
by: Sprigg, Nikola, et al.
Published: (2007)

Risk of venous thromboembolism in people with lung cancer: a cohort study using linked UK healthcare data
by: Walker, Alex J., et al.
Published: (2016)

Anticoagulant activity and toxicity profiles of Melastoma malabathricum linn. leaf extract
by: Manicam, Caroline
Published: (2011)

Bioassay-guided fractionation of anticoagulant compounds from Melastoma malabathricum Linn. Leaf
by: Khoo, Li Teng
Published: (2015)

An automated software system to promote anticoagulation and reduce stroke risk: cluster-randomized controlled trial
by: Holt, Tim A., et al.
Published: (2017)

Venous thromboembolism and mortality in breast cancer: cohort study with systematic review and meta-analysis
by: Khan, Umair T., et al.
Published: (2017)

Development of a European Organization for research and treatment of Cancer Module to Assess the Quality of Life of Patients with Proctitis after Pelvic Radiotherapy for Malignancy
by: Spry, N., et al.
Published: (2008)

Remote assessment of platelet function in patients with acute stroke or transient ischaemic attack
by: Bath, Philip M.W., et al.
Published: (2017)

Sex differences in quality of life in stroke survivors. Data from the Tinzaparin in Acute Ischaemic Stroke Trial (TAIST)
by: Gray, Laura J., et al.
Published: (2007)

The Insulin Resistance Intervention after Stroke trial: a perspective on future practice and research
by: Bath, Philip M.W., et al.
Published: (2016)

Developing and trialling a school-based ovulatory-menstrual health literacy programme for adolescent girls: A quasi-experimental mixed-method protocol
by: Roux, Felicity, et al.
Published: (2019)

Effects of secondary poisoning from anticoagulant and biological rodenticides on barn owl, Tyto alba javanica, in an immature oil palm plantation
by: Trubus , Mohd. Na'im
Published: (2011)

Exposure to bisphosphonates and risk of cancer: a protocol for nested caseecontrol studies using the QResearch primary care database
by: Vinogradova, Yana, et al.
Published: (2012)

Exposure to bisphosphonates and risk of common non-gastrointestinal cancers: series of nested case–control studies using two primary-care databases
by: Vinogradova, Yana, et al.
Published: (2013)

Remote ischaemic conditioning: individual patient data meta-analysis of acute stroke trials and prospective MRI evaluation in healthy adults
by: Dhillon, Permesh Singh
Published: (2021)

The pattern of underlying cause of death in patients with inflammatory bowel disease in England: a record linkage study
by: Chu, Thomas P.C., et al.
Published: (2016)

A validation study of the CirCom comorbidity score in an English cirrhosis population using the Clinical Practice Research Datalink
by: Crooks, Colin J., et al.
Published: (2018)

Bleeding Severity in Percutaneous Coronary Intervention (PCI) and Its Impact on Short-Term Clinical Outcomes
by: Murali, Shashank, et al.
Published: (2020)

Do men know which lower bowel symptoms warrant medical attention? A web-based video vignette survey of men in Western Australia
by: Oberoi, Devesh Varun, et al.
Published: (2015)

Brave new world inches closer
by: Leslie, Gavin
Published: (2004)

Discontinuation and restarting in patients on statin therapy: a cohort study using a primary care database
by: Vinogradova, Yana, et al.
Published: (2016)