A facile route to bespoke macro- and mesoporous block copolymer microparticles

We report a facile and versatile strategy for the bespoke fabrication of macro- and mesoporous block copolymer microparticles. A clean synthetic route, RAFT dispersion polymerisation in supercritical carbon dioxide (scCO2), is used to generate block copolymer microparticles. Selective swelling/deswe...

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Main Authors: He, Guping, Bennett, Thomas M., Alauhdin, Mohammad, Fay, Michael W., Liu, Xin, Schwab, Simon T., Sun, Cheng-gong, Howdle, Steven M.
Format: Article
Published: Royal Society of Chemistry 2018
Online Access:https://eprints.nottingham.ac.uk/52916/
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author He, Guping
Bennett, Thomas M.
Alauhdin, Mohammad
Fay, Michael W.
Liu, Xin
Schwab, Simon T.
Sun, Cheng-gong
Howdle, Steven M.
author_facet He, Guping
Bennett, Thomas M.
Alauhdin, Mohammad
Fay, Michael W.
Liu, Xin
Schwab, Simon T.
Sun, Cheng-gong
Howdle, Steven M.
author_sort He, Guping
building Nottingham Research Data Repository
collection Online Access
description We report a facile and versatile strategy for the bespoke fabrication of macro- and mesoporous block copolymer microparticles. A clean synthetic route, RAFT dispersion polymerisation in supercritical carbon dioxide (scCO2), is used to generate block copolymer microparticles. Selective swelling/deswelling is then applied to induce controlled morphology transitions and to trap the resulting porous state. The pore sizes are controllable over a large size range (~20 – 200 nm) by varying the length of the swellable block. Through a systematic approach we then demonstrate that the shape of the pores can also be tailored from isolated spheres through to interconnected/bicontinuous channels by varying the ratio of the two blocks. This process is shown to be applicable to a range of poly(methyl methacrylate) (PMMA)based block copolymer systems, including PMMA-b-poly(4-vinyl pyridine), PMMAb-poly(dimethyl acrylamide) (DMA) and PMMA-bpoly(dimethylaminoethylmethacrylate) (DMAEMA). In each case, the second minority block (e.g. P4VP, etc.) was selectively swollen with an alcohol to induce an order-toorder morphology transition and then quenched rapidly by the non-solvent hexane. This not only takes place on the order of hours, but is also freely scalable for the production of grams of material and beyond in a single step following polymerisation.
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spelling nottingham-529162020-05-04T19:40:46Z https://eprints.nottingham.ac.uk/52916/ A facile route to bespoke macro- and mesoporous block copolymer microparticles He, Guping Bennett, Thomas M. Alauhdin, Mohammad Fay, Michael W. Liu, Xin Schwab, Simon T. Sun, Cheng-gong Howdle, Steven M. We report a facile and versatile strategy for the bespoke fabrication of macro- and mesoporous block copolymer microparticles. A clean synthetic route, RAFT dispersion polymerisation in supercritical carbon dioxide (scCO2), is used to generate block copolymer microparticles. Selective swelling/deswelling is then applied to induce controlled morphology transitions and to trap the resulting porous state. The pore sizes are controllable over a large size range (~20 – 200 nm) by varying the length of the swellable block. Through a systematic approach we then demonstrate that the shape of the pores can also be tailored from isolated spheres through to interconnected/bicontinuous channels by varying the ratio of the two blocks. This process is shown to be applicable to a range of poly(methyl methacrylate) (PMMA)based block copolymer systems, including PMMA-b-poly(4-vinyl pyridine), PMMAb-poly(dimethyl acrylamide) (DMA) and PMMA-bpoly(dimethylaminoethylmethacrylate) (DMAEMA). In each case, the second minority block (e.g. P4VP, etc.) was selectively swollen with an alcohol to induce an order-toorder morphology transition and then quenched rapidly by the non-solvent hexane. This not only takes place on the order of hours, but is also freely scalable for the production of grams of material and beyond in a single step following polymerisation. Royal Society of Chemistry 2018-06-15 Article PeerReviewed He, Guping, Bennett, Thomas M., Alauhdin, Mohammad, Fay, Michael W., Liu, Xin, Schwab, Simon T., Sun, Cheng-gong and Howdle, Steven M. (2018) A facile route to bespoke macro- and mesoporous block copolymer microparticles. Polymer Chemistry, 9 (27). p. 3808. ISSN 1759-9954 http://pubs.rsc.org/en/Content/ArticleLanding/2018/PY/C8PY00707A#!divAbstract doi:10.1039/c8py00707a doi:10.1039/c8py00707a
spellingShingle He, Guping
Bennett, Thomas M.
Alauhdin, Mohammad
Fay, Michael W.
Liu, Xin
Schwab, Simon T.
Sun, Cheng-gong
Howdle, Steven M.
A facile route to bespoke macro- and mesoporous block copolymer microparticles
title A facile route to bespoke macro- and mesoporous block copolymer microparticles
title_full A facile route to bespoke macro- and mesoporous block copolymer microparticles
title_fullStr A facile route to bespoke macro- and mesoporous block copolymer microparticles
title_full_unstemmed A facile route to bespoke macro- and mesoporous block copolymer microparticles
title_short A facile route to bespoke macro- and mesoporous block copolymer microparticles
title_sort facile route to bespoke macro- and mesoporous block copolymer microparticles
url https://eprints.nottingham.ac.uk/52916/
https://eprints.nottingham.ac.uk/52916/
https://eprints.nottingham.ac.uk/52916/