RubiX: combining spatial resolutions for Bayesian inference of crossing fibers in diffusion MRI
The trade-off between signal-to-noise ratio (SNR) and spatial specificity governs the choice of spatial resolution in magnetic resonance imaging (MRI); diffusion-weighted (DW) MRI is no exception. Images of lower resolution have higher signal to noise ratio, but also more partial volume artifacts. W...
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| Format: | Article |
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Institute of Electrical and Electronics Engineers
2013
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| Online Access: | https://eprints.nottingham.ac.uk/52888/ |
| _version_ | 1848798833142661120 |
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| author | Sotiropoulos, S.N. Jbabdi, S. Andersson, J.L. Woolrich, M.W. Ugurbil, K. Behrens, T.E.J. |
| author_facet | Sotiropoulos, S.N. Jbabdi, S. Andersson, J.L. Woolrich, M.W. Ugurbil, K. Behrens, T.E.J. |
| author_sort | Sotiropoulos, S.N. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | The trade-off between signal-to-noise ratio (SNR) and spatial specificity governs the choice of spatial resolution in magnetic resonance imaging (MRI); diffusion-weighted (DW) MRI is no exception. Images of lower resolution have higher signal to noise ratio, but also more partial volume artifacts. We present a data-fusion approach for tackling this trade-off by combining DW MRI data acquired both at high and low spatial resolution. We combine all data into a single Bayesian model to estimate the underlying fiber patterns and diffusion parameters. The proposed model, therefore, combines the benefits of each acquisition. We show that fiber crossings at the highest spatial resolution can be inferred more robustly and accurately using such a model compared to a simpler model that operates only on high-resolution data, when both approaches are matched for acquisition time. |
| first_indexed | 2025-11-14T20:26:03Z |
| format | Article |
| id | nottingham-52888 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T20:26:03Z |
| publishDate | 2013 |
| publisher | Institute of Electrical and Electronics Engineers |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-528882020-05-04T16:36:44Z https://eprints.nottingham.ac.uk/52888/ RubiX: combining spatial resolutions for Bayesian inference of crossing fibers in diffusion MRI Sotiropoulos, S.N. Jbabdi, S. Andersson, J.L. Woolrich, M.W. Ugurbil, K. Behrens, T.E.J. The trade-off between signal-to-noise ratio (SNR) and spatial specificity governs the choice of spatial resolution in magnetic resonance imaging (MRI); diffusion-weighted (DW) MRI is no exception. Images of lower resolution have higher signal to noise ratio, but also more partial volume artifacts. We present a data-fusion approach for tackling this trade-off by combining DW MRI data acquired both at high and low spatial resolution. We combine all data into a single Bayesian model to estimate the underlying fiber patterns and diffusion parameters. The proposed model, therefore, combines the benefits of each acquisition. We show that fiber crossings at the highest spatial resolution can be inferred more robustly and accurately using such a model compared to a simpler model that operates only on high-resolution data, when both approaches are matched for acquisition time. Institute of Electrical and Electronics Engineers 2013-05-29 Article PeerReviewed Sotiropoulos, S.N., Jbabdi, S., Andersson, J.L., Woolrich, M.W., Ugurbil, K. and Behrens, T.E.J. (2013) RubiX: combining spatial resolutions for Bayesian inference of crossing fibers in diffusion MRI. IEEE Transactions on Medical Imaging, 32 (6). pp. 969-982. ISSN 0278-0062 https://ieeexplore.ieee.org/document/6420959/ doi:10.1109/TMI.2012.2231873 doi:10.1109/TMI.2012.2231873 |
| spellingShingle | Sotiropoulos, S.N. Jbabdi, S. Andersson, J.L. Woolrich, M.W. Ugurbil, K. Behrens, T.E.J. RubiX: combining spatial resolutions for Bayesian inference of crossing fibers in diffusion MRI |
| title | RubiX: combining spatial resolutions for Bayesian inference of crossing fibers in diffusion MRI |
| title_full | RubiX: combining spatial resolutions for Bayesian inference of crossing fibers in diffusion MRI |
| title_fullStr | RubiX: combining spatial resolutions for Bayesian inference of crossing fibers in diffusion MRI |
| title_full_unstemmed | RubiX: combining spatial resolutions for Bayesian inference of crossing fibers in diffusion MRI |
| title_short | RubiX: combining spatial resolutions for Bayesian inference of crossing fibers in diffusion MRI |
| title_sort | rubix: combining spatial resolutions for bayesian inference of crossing fibers in diffusion mri |
| url | https://eprints.nottingham.ac.uk/52888/ https://eprints.nottingham.ac.uk/52888/ https://eprints.nottingham.ac.uk/52888/ |