The topographic connectome
Central to macro-connectomics and much of systems neuroscience is the idea that we can summarise macroscopic brain connectivity using a network of ‘nodes’ and ‘edges’ — functionally distinct brain regions and the connections between them. This is an approach that allows a deep understanding of brain...
| Main Authors: | , , |
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| Format: | Article |
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Elsevier
2013
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| Online Access: | https://eprints.nottingham.ac.uk/52879/ |
| _version_ | 1848798831297167360 |
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| author | Jbabdi, Saad Sotiropoulos, Stamatios N. Behrens, Timothy E. |
| author_facet | Jbabdi, Saad Sotiropoulos, Stamatios N. Behrens, Timothy E. |
| author_sort | Jbabdi, Saad |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Central to macro-connectomics and much of systems neuroscience is the idea that we can summarise macroscopic brain connectivity using a network of ‘nodes’ and ‘edges’ — functionally distinct brain regions and the connections between them. This is an approach that allows a deep understanding of brain dynamics and how they relate to brain circuitry. This approach, however, ignores key features of anatomical connections, such as spatial arrangement and topographic mappings. In this article, we suggest an alternative to this paradigm. We propose that connection topographies can inform us about brain networks in ways that are complementary to the concepts of ‘nodes’ and ‘edges’. We also show that current neuroimaging technology is capable of revealing details of connection topographies in vivo. These advances, we hope, will allow us to explore brain connectivity in novel ways in the immediate future. |
| first_indexed | 2025-11-14T20:26:01Z |
| format | Article |
| id | nottingham-52879 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T20:26:01Z |
| publishDate | 2013 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-528792020-05-04T16:36:15Z https://eprints.nottingham.ac.uk/52879/ The topographic connectome Jbabdi, Saad Sotiropoulos, Stamatios N. Behrens, Timothy E. Central to macro-connectomics and much of systems neuroscience is the idea that we can summarise macroscopic brain connectivity using a network of ‘nodes’ and ‘edges’ — functionally distinct brain regions and the connections between them. This is an approach that allows a deep understanding of brain dynamics and how they relate to brain circuitry. This approach, however, ignores key features of anatomical connections, such as spatial arrangement and topographic mappings. In this article, we suggest an alternative to this paradigm. We propose that connection topographies can inform us about brain networks in ways that are complementary to the concepts of ‘nodes’ and ‘edges’. We also show that current neuroimaging technology is capable of revealing details of connection topographies in vivo. These advances, we hope, will allow us to explore brain connectivity in novel ways in the immediate future. Elsevier 2013-04-30 Article PeerReviewed Jbabdi, Saad, Sotiropoulos, Stamatios N. and Behrens, Timothy E. (2013) The topographic connectome. Current Opinion in Neurobiology, 23 (2). pp. 207-215. ISSN 0959-4388 https://www.sciencedirect.com/science/article/pii/S0959438812001936?via%3Dihub doi:10.1016/j.conb.2012.12.004 doi:10.1016/j.conb.2012.12.004 |
| spellingShingle | Jbabdi, Saad Sotiropoulos, Stamatios N. Behrens, Timothy E. The topographic connectome |
| title | The topographic connectome |
| title_full | The topographic connectome |
| title_fullStr | The topographic connectome |
| title_full_unstemmed | The topographic connectome |
| title_short | The topographic connectome |
| title_sort | topographic connectome |
| url | https://eprints.nottingham.ac.uk/52879/ https://eprints.nottingham.ac.uk/52879/ https://eprints.nottingham.ac.uk/52879/ |