DNA replication roadblocks caused by Cascade Interference complexes are alleviated by RecG DNA repair helicase

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DNA replication roadblocks caused by Cascade Interference complexes are alleviated by RecG DNA repair helicase

Cascade complexes underpin E. coli CRISPR-Cas immunity systems by stimulating "adaptation" reactions that update immunity and by initiating "interference" reactions that destroy invader DNA. Recognition of invader DNA in Cascade catalysed R-loops provokes DNA capture and its subs...

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Bibliographic Details
Main Authors:	Killelea, Tom, Hawkins, Michelle, Howard, Jamieson, McGlynn, Peter, Bolt, Edward L.
Format:	Article
Published:	Taylor & Francis 2018
Online Access:	https://eprints.nottingham.ac.uk/52737/

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