Immunization with a DNA vaccine cocktail encoding TgPF, TgROP16, TgROP18, TgMIC6, and TgCDPK3 genes protects mice against chronic toxoplasmosis

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Immunization with a DNA vaccine cocktail encoding TgPF, TgROP16, TgROP18, TgMIC6, and TgCDPK3 genes protects mice against chronic toxoplasmosis

Toxoplasmosis is a zoonotic disease caused by the intracellular protozoan Toxoplasma gondii; and a major source of infection in humans is via ingestion of T. gondii tissue cysts. Ultimately, the goal of anti-toxoplasmosis vaccines is to elicit a sustainable immune response, capable of preventing for...

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Bibliographic Details
Main Authors:	Zhang, Nian-Zhang, Gao, Qi, Wang, Meng, Elsheikha, Hany M., Wang, Bo, Wang, Jin-Lei, Zhang, Fu-Kai, Hu, Ling-Ying, Zhu, Xing-Quan
Format:	Article
Published:	Frontiers Media 2018
Subjects:	Toxoplasma gondii chronic toxoplasmosis cocktail DNA vaccine multistage antigens mixed Th1/Th2 immune response
Online Access:	https://eprints.nottingham.ac.uk/52694/

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