Structural variations in hyperbranched polymers prepared via thermal polycondensation of lysine and histidine and their effects on DNA delivery

QR Code

Structural variations in hyperbranched polymers prepared via thermal polycondensation of lysine and histidine and their effects on DNA delivery

The successful clinical translation of non-viral gene delivery systems has yet to be achieved due to the biological and technical obstacles to preparing a safe, potent and cost-effective vector. Hyper-branched polymers have emerged as promising candidates to address gene delivery barriers owing to t...

Full description

Bibliographic Details
Main Authors:	Alazzo, Ali, Lovato, Tatiana, Collins, Hilary M., Taresco, Vincenzo, Stolnik, Snjezana, Soliman, Mahmoud E., Spriggs, Keith, Alexander, Cameron
Format:	Article
Published:	Wiley 2018
Online Access:	https://eprints.nottingham.ac.uk/52559/

Similar Items

Rapid formulation of redox-responsive oligo-β-aminoester polyplexes with siRNA via jet printing
by: Lovato, Tatiana, et al.
Published: (2018)

Hyperbranched polymers as non-viral vectors for gene delivery
by: Alazzo, Ali
Published: (2018)

Enhanced uptake in 2D- and 3D- lung cancer cell models of redox responsive PEGylated nanoparticles with sensitivity to reducing extra-and intracellular environments
by: Conte, Claudia, et al.
Published: (2018)

A concise review on microwave-assisted polycondensation reactions and curing of polycondensation polymers with focus on the effect of process conditions
by: Komorowska-Durka, M., et al.
Published: (2014)

Stimuli-responsive prodrug chemistries for drug delivery
by: Taresco, Vincenzo, et al.
Published: (2018)

Biocompatible hyperbranched polyglycerol modified ß-cyclodextrin derivatives for docetaxel delivery
by: Xu, Z., et al.
Published: (2017)

Self-catalyzed polycondensation between polyols and dicarboxylic acids
by: Lim, Rui Rui
Published: (2015)

Star-Shaped Amphiphilic Hyperbranched Polyglycerol Conjugated with Dendritic Poly(l-lysine) for the Codelivery of Docetaxel and MMP-9 siRNA in Cancer Therapy.
by: Zhou, X., et al.
Published: (2016)

Microwave-assisted polymer synthesis of polycondensation materials for high performance coatings
by: Vidales Herrera, Jessica Vidales
Published: (2023)

Water solubility enhancement of pyrazolo[3,4-d]pyrimidine derivatives via miniaturized polymer-drug microarrays
by: Sanna, Monica, et al.
Published: (2018)

Synthesis and application of novel hyperbranched polymers
by: Goodwin, Sophie, R
Published: (2021)

Preparation of hyperbranched polymers by controlled/living polymerisations
by: Zheng, Yu
Published: (2010)

Modification of NanoCrystalline Cellulose (NCC) by Hyperbranched Polymer
by: Zianor Azrina, Z. A., et al.
Published: (2017)

The lysine response of the turkey
by: Nixey, Clifford
Published: (1991)

Histidine-based copper tetrapeptides as enantioselective catalysts for aldol reactions
by: Begum, Sharifa Zaithun, et al.
Published: (2018)

Star-shaped poly(oligoethylene glycol) copolymer-based gels: thermo-responsive behaviour and bioapplicability for risedronate intranasal delivery
by: Soliman, Mahmoud E., et al.
Published: (2018)

Low-temperature quartz wafer bonding using hyperbranched polyurethane oligomers
by: Zhao, J., et al.
Published: (2014)

Exploring the Role of ARABIDOPSIS HISTIDINE PHOSPHOTRANSFERASE 4 (AHP4) in Cytokinin Signalling
by: Chrysanthou, Elina
Published: (2023)

Poly-L-lysine functionalized large pore cubic mesostructured silica nanoparticles as biocompatible carriers for gene delivery
by: Hartono, S., et al.
Published: (2012)

Hyperbranched polyethyleneimine induced polycationic membranes for improved fouling resistance and high RO performance
by: Aneela, Sabir, et al.
Published: (2016)

Lysine availability in protein-alginate ester gels
by: Mohamed, Suhaila, et al.
Published: (1984)

Purification of histidine-tagged nucleocapsid protein of Nipah virus using immobilized metal affinity chromatography
by: Fui , Chin Chong, et al.
Published: (2009)

Removal of poly-histidine fusion tags from recombinant proteins purified by expanded bed adsorption
by: Abdullah, Norhafizah, et al.
Published: (2005)

Bioreducible cross-linked core polymer micelles enhance in vitro activity of methotrexate in breast cancer cells
by: Gulfam, Muhammad, et al.
Published: (2017)

Preparation and characterisation of hyperbranched poly divinyl benzene and star branched poly lactic acid blends and their composites
by: Kabir, Sumaya Farhana
Published: (2017)

Recovery of histidine-tagged nucleocapsid protein of Newcastle disease virus using immobilised metal affinity chromatography
by: Tan, Yan Peng, et al.
Published: (2006)

Thiocolchicoside ameliorated glycation via lysine blockade and carbonyl entrapment
by: Khatian, Najeeb, et al.
Published: (2025)

Development of chimeric lysins to elucidate the utility of sortase directed enzybiotics
by: Newman, Robert
Published: (2020)

Screening and characterisation of lactic acid bacteria and substrates for lysine production
by: Toe, Cui Jin
Published: (2017)

Hydrodynamics of the VanA-type VanS histidine kinase: an extended solution conformation and first evidence for interactions with vancomycin
by: Phillips-Jones, Mary K., et al.
Published: (2017)

Experimental evaluation on surface plasmon resonance sensor performance based on sensitive hyperbranched polymer nanocomposite thin films
by: Sheh Omar, Nur Alia, et al.
Published: (2020)

Identification of novel ‘inks’ for 3D printing using high throughput screening: bioresorbable photocurable polymers for controlled drug delivery
by: Louzao, Iria, et al.
Published: (2018)

Carbene in cupredoxin protein scaffolds: replacement of a histidine ligand in the active site substantially alters copper redox properties
by: Planchestainer, Matteo, et al.
Published: (2018)

Combining thio-bromo Click chemistry and raft polymerization: a powerful tool for preparing functionalized multiblock and hyperbranched polymers
by: Xu, J., et al.
Published: (2010)

In Vitro Selection In Wheat To Recover Mutants Which Overproduce Lysine And Threonine
by: Abdul Kadir, Midhzar
Published: (1991)

Construction of a High-Efficiency Drug and Gene Co-Delivery System for Cancer Therapy from a pH-Sensitive Supramolecular Inclusion between Oligoethylenimine- graft-ß-cyclodextrin and Hyperbranched Polyglycerol Derivative
by: Zhou, X., et al.
Published: (2018)

Properties of acyl modified poly(glycerol-adipate) comb-like polymers and their self-assembly into nanoparticles
by: Taresco, Vincenzo, et al.
Published: (2016)

Histidine146 of Human Serum Albumin Plays a Prominent Role at the Interface of Subdomains IA and IIA in Allosteric Ligand Binding
by: Kaneko, K., et al.
Published: (2011)

Functional expression, purification, biochemical and biophysical characterizations, and molecular dynamics simulation of a histidine acid phosphatase from Saccharomyces cerevisiae
by: Nezhad, Nima Ghahremani, et al.
Published: (2024)

Functional expression, purification, biochemical and biophysical characterizations, and molecular dynamics simulation of a histidine acid phosphatase from Saccharomyces cerevisiae
by: Nezhad, Nima Ghahremani, et al.
Published: (2024)