Handgrip strength cannot be assumed a proxy for overall muscle strength
Objectives: Dynapenia, low muscle strength, is predictive for negative health outcomes and is usually expressed as handgrip strength (HGS). Whether HGS can be a proxy for overall muscle strength and whether this depends on age and health status is controversial. This study assessed the agreement bet...
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| Format: | Article |
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Elsevier
2018
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| Online Access: | https://eprints.nottingham.ac.uk/52547/ |
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| author | Yeung, Suey S.Y. Reijnierse, Esmee M. Trappenburg, Marijke C. Hogrel, Jean-Yves McPhee, Jamie S. Piasecki, Mathew Sipila, Sarianna Salpakoski, Anu Butler-Browne, Gillian Pääsuke, Mati Gapeyeva, Helena Narici, Marco V. Meskers, Carel G.M. Maier, Andrea B. |
| author_facet | Yeung, Suey S.Y. Reijnierse, Esmee M. Trappenburg, Marijke C. Hogrel, Jean-Yves McPhee, Jamie S. Piasecki, Mathew Sipila, Sarianna Salpakoski, Anu Butler-Browne, Gillian Pääsuke, Mati Gapeyeva, Helena Narici, Marco V. Meskers, Carel G.M. Maier, Andrea B. |
| author_sort | Yeung, Suey S.Y. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Objectives: Dynapenia, low muscle strength, is predictive for negative health outcomes and is usually expressed as handgrip strength (HGS). Whether HGS can be a proxy for overall muscle strength and whether this depends on age and health status is controversial. This study assessed the agreement between HGS and knee extension strength (KES) in populations differing in age and health status.
Design: Data were retrieved from 5 cohorts.
Setting and Participants: Community, geriatric outpatient clinics, and a hospital. Five cohorts (960 individuals, 49.8% male) encompassing healthy young and older individuals, geriatric outpatients, and older individuals post hip fracture were included.
Measures: HGS and KES were measured according to the protocol of each cohort. Pearson correlation was performed to analyze the association between HGS and KES, stratified by sex. HGS and KES were standardized into sex-specific z scores. The agreement between standardized HGS and standardized KES at population level and individual level were assessed by intraclass correlation coefficients (ICC) and Bland-Altman analysis.
Results: Pearson correlation coefficients were low in healthy young (male: 0.36 to 0.45, female: 0.45) and healthy older individuals (male: 0.35 to 0.37, female: 0.44), and moderate in geriatric outpatients (male and female: 0.54) and older individuals post hip fracture (male: 0.44, female: 0.57) (P<.05, except for male older individuals post hip fracture [P¼.07]). Intraclass correlation coefficient values were poor to moderate in all populations (ie, healthy young individuals [0.41, 0.45], healthy older individuals [0.37, 0.41, 0.44], geriatric outpatients [0.54], and older individuals post hip fracture [0.54]). Bland-Altman analysis showed that within the same population of age and health status, agreement between HGS and KES varied on individual level. |
| first_indexed | 2025-11-14T20:24:44Z |
| format | Article |
| id | nottingham-52547 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T20:24:44Z |
| publishDate | 2018 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-525472024-08-15T15:29:59Z https://eprints.nottingham.ac.uk/52547/ Handgrip strength cannot be assumed a proxy for overall muscle strength Yeung, Suey S.Y. Reijnierse, Esmee M. Trappenburg, Marijke C. Hogrel, Jean-Yves McPhee, Jamie S. Piasecki, Mathew Sipila, Sarianna Salpakoski, Anu Butler-Browne, Gillian Pääsuke, Mati Gapeyeva, Helena Narici, Marco V. Meskers, Carel G.M. Maier, Andrea B. Objectives: Dynapenia, low muscle strength, is predictive for negative health outcomes and is usually expressed as handgrip strength (HGS). Whether HGS can be a proxy for overall muscle strength and whether this depends on age and health status is controversial. This study assessed the agreement between HGS and knee extension strength (KES) in populations differing in age and health status. Design: Data were retrieved from 5 cohorts. Setting and Participants: Community, geriatric outpatient clinics, and a hospital. Five cohorts (960 individuals, 49.8% male) encompassing healthy young and older individuals, geriatric outpatients, and older individuals post hip fracture were included. Measures: HGS and KES were measured according to the protocol of each cohort. Pearson correlation was performed to analyze the association between HGS and KES, stratified by sex. HGS and KES were standardized into sex-specific z scores. The agreement between standardized HGS and standardized KES at population level and individual level were assessed by intraclass correlation coefficients (ICC) and Bland-Altman analysis. Results: Pearson correlation coefficients were low in healthy young (male: 0.36 to 0.45, female: 0.45) and healthy older individuals (male: 0.35 to 0.37, female: 0.44), and moderate in geriatric outpatients (male and female: 0.54) and older individuals post hip fracture (male: 0.44, female: 0.57) (P<.05, except for male older individuals post hip fracture [P¼.07]). Intraclass correlation coefficient values were poor to moderate in all populations (ie, healthy young individuals [0.41, 0.45], healthy older individuals [0.37, 0.41, 0.44], geriatric outpatients [0.54], and older individuals post hip fracture [0.54]). Bland-Altman analysis showed that within the same population of age and health status, agreement between HGS and KES varied on individual level. Elsevier 2018-06-20 Article PeerReviewed Yeung, Suey S.Y., Reijnierse, Esmee M., Trappenburg, Marijke C., Hogrel, Jean-Yves, McPhee, Jamie S., Piasecki, Mathew, Sipila, Sarianna, Salpakoski, Anu, Butler-Browne, Gillian, Pääsuke, Mati, Gapeyeva, Helena, Narici, Marco V., Meskers, Carel G.M. and Maier, Andrea B. (2018) Handgrip strength cannot be assumed a proxy for overall muscle strength. Journal of the American Medical Directors Association . ISSN 1538-9375 Muscle strength; knee extension strength; aged; geriatric assessment https://www.sciencedirect.com/science/article/pii/S1525861018302366 doi:10.1016/j.jamda.2018.04.019 doi:10.1016/j.jamda.2018.04.019 |
| spellingShingle | Muscle strength; knee extension strength; aged; geriatric assessment Yeung, Suey S.Y. Reijnierse, Esmee M. Trappenburg, Marijke C. Hogrel, Jean-Yves McPhee, Jamie S. Piasecki, Mathew Sipila, Sarianna Salpakoski, Anu Butler-Browne, Gillian Pääsuke, Mati Gapeyeva, Helena Narici, Marco V. Meskers, Carel G.M. Maier, Andrea B. Handgrip strength cannot be assumed a proxy for overall muscle strength |
| title | Handgrip strength cannot be assumed a proxy for overall muscle strength |
| title_full | Handgrip strength cannot be assumed a proxy for overall muscle strength |
| title_fullStr | Handgrip strength cannot be assumed a proxy for overall muscle strength |
| title_full_unstemmed | Handgrip strength cannot be assumed a proxy for overall muscle strength |
| title_short | Handgrip strength cannot be assumed a proxy for overall muscle strength |
| title_sort | handgrip strength cannot be assumed a proxy for overall muscle strength |
| topic | Muscle strength; knee extension strength; aged; geriatric assessment |
| url | https://eprints.nottingham.ac.uk/52547/ https://eprints.nottingham.ac.uk/52547/ https://eprints.nottingham.ac.uk/52547/ |