Circulating biomarkers during treatment in patients with advanced biliary tract cancer receiving cediranib in the UK ABC-03 trial

QR Code

Circulating biomarkers during treatment in patients with advanced biliary tract cancer receiving cediranib in the UK ABC-03 trial

BACKGROUND: Advanced biliary tract cancer (ABC) has a poor prognosis. Cediranib, in addition to cisplatin/gemcitabine [CisGem], improved the response rate, but did not improve the progression-free survival (PFS) in the ABC-03 study. Minimally invasive biomarkers predictive of cediranib benefit may i...

Full description

Bibliographic Details
Main Authors:	Backen, Alison C., Lopes, Andre, Wasan, Harpreet, Palmer, Daniel H., Duggan, Marian, Cunningham, David, Anthoney, Alan, Corrie, Pippa G., Madhusudan, Srinivasan, Maraveyas, Anthony, Ross, Paul J., Waters, Justin S., Steward, William P., Rees, Charlotte, McNamara, Mairéad G., Beare, Sandy, Bridgewater, John A., Dive, Caroline, Valle, Juan W.
Format:	Article
Published:	2018
Online Access:	https://eprints.nottingham.ac.uk/52543/

Similar Items

Cediranib or placebo in combination with cisplatin and gemcitabine chemotherapy for patients with advanced biliary tract cancer (ABC-03): a randomised phase 2 trial
by: Valle, Juan W., et al.
Published: (2015)

A preliminary study of ultrasonographic appearances of gall bladder and biliary tract in clinically suspected biliary atresia
by: Yusoff, Wan Norhayati Wan
Published: (2006)

Ultrasound features in the diagnosis of biliary atresia
by: Khim, Sim See
Published: (2017)

Cediranib in combination with fulvestrant in hormone-sensitive metastatic breast cancer: a randomized Phase 11 study
by: Hyams, D., et al.
Published: (2013)

Modeling of the biliary tree structure in MRCP images
by: Logeswaran, , Rajasvaran, et al.
Published: (2005)

Ampullary carcinoma: effect of preoperative biliary drainage on surgical outcome
by: Abdullah, Sheikh Anwar, et al.
Published: (2009)

Scale-space segment growing for hierarchical detection of biliary tree structure
by: LOGESWARAN, RAJASVARAN
Published: (2005)

Biliary ascariasis from a rural setting: a case study.
by: Sai Sanjeev, M, et al.
Published: (2012)

Congenital biliary anomaly with secondary cholangiohepatitis in a Siamese cross kitten
by: Yiew, Xiu Ting, et al.
Published: (2016)

Computer-Aided Detection, Modelling And Diagnostic Techniques For Biliary Structure Using MRCP
by: Logeswaran., R.
Published: (2006)

Patient-specific 3D printed model of biliary ducts with congenital cyst
by: Allan, A., et al.
Published: (2019)

Surgical management of biliary duct hamartoma in a cat: a case report
by: Ab Manap, Nur Ainina, et al.
Published: (2025)

Reconstruction of biliary structure in 2D MRCP images using multi-scale analysis
by: LOGESWARAN, R
Published: (2008)

Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids
by: Sampaziotis, Fotios, et al.
Published: (2017)

Impact of cholangioscopy: diagnosing sclerosing cholangitis-associated biliary calculi not detected using MRI and endoscopic ultrasound
by: Fateen, Waleed, et al.
Published: (2018)

Peak inflammation in atherosclerosis, primary biliary cirrhosis and autoimmune arthritis is counter-intuitively associated with regulatory T cell enrichment
by: Garetto, S., et al.
Published: (2015)

Diagnostic Efficacy of Advanced Ultrasonography Imaging Techniques in Infants with Biliary Atresia (BA): A Systematic Review and Meta-Analysis
by: Gunda, Simon Takadiyi, et al.
Published: (2022)

Taurocholate Induces Biliary Differentiation of Liver Progenitor Cells Causing Hepatic Stellate Cell Chemotaxis in the Ductular Reaction: Role in Pediatric Cystic Fibrosis Liver Disease
by: Pozniak, K., et al.
Published: (2017)

Vandetanib plus gemcitabine versus placebo plus gemcitabine in locally advanced or metastatic pancreatic carcinoma (ViP): a prospective, randomised, double-blind, multicentre phase 2 trial
by: Middleton, Gary, et al.
Published: (2017)

Start-up firms. Strategic or suck-it-and-see? A qualitative study of how fledgling firms in the East Midlands region of the United Kingdom use strategic entrepreneurship to gain competitive advantage.
by: Anthoney, Julian
Published: (2012)

English language vocabulary learning strategies employed by young ESL learners / Harpreet Kaur
by: Harpreet , Kaur
Published: (2019)

Social development and social policy in Guinea: health and education 1958-1984
by: Corrie, Elizabeth M.
Published: (1988)

Establishment of a resilient modulus test for evaluating reduced size asphalt mixture
by: Anthoney, Francis Xavier
Published: (2019)

Economics of a Single Currency
by: Sachdev, Harpreet Kaur
Published: (2007)

Valuing Real Estate Investments
by: Chadha, Harpreet Singh
Published: (2009)

Gemcitabine and capecitabine with or without telomerase peptide vaccine GV1001 in patients with locally advanced or metastatic pancreatic cancer (TeloVac): an open-label, randomised, phase 3 trial
by: Middleton, Gary, et al.
Published: (2014)

Peribahasa Iban Terpilih: Analisis Berdasarkan Teori Etika Kewajipan Prima Facie
by: Mingat, Steward Rickyues
Published: (2019)

An analysis of grammatical and lexical cohesion in oral communication among Japanese language learners in university
by: Anthoney, Margaret, et al.
Published: (2022)

The ABCs of reading an ECG
by: Shalihin, Mohd Shaiful Ehsan
Published: (2015)

ABCs of chest radiography
by: Hassan, Radhiana
Published: (2019)

Adding the "ABC" to the "STEM"
by: Sim, Tze Ying *
Published: (2019)

Interview on ABC Focus
by: Rich, Ben
Published: (2018)

Interview with ABC the Signal
by: Rich, Ben
Published: (2018)

The ABC’s of PhD
by: Jusoff, Kamaruzaman, et al.
Published: (2010)

Effect of water-soluble gummy fiber, water-insoluble neutral detergent fiber isolated from Syzygium cumini seeds on biliary and fecal bile acids and sterols in rats fed a high cholesterol diet
by: Madhuri A Agnihotri,, et al.
Published: (2015)

Investigational ABC transporter inhibitors
by: Falasca, Marco, et al.
Published: (2012)

Developing a Strategy for Cardiovascular Disease: Surveillance,Prevention and Healthcare.
by: William, Cairns Steward Smith
Published: (2014)

An ABC of apolipoprotein C-III: a clinically useful new cardiovascular risk factor?
by: Chan, D., et al.
Published: (2008)

An exploration of nursing research perceptions of registered nurses engaging in research activities at a metropolitan hospital in Western Australia
by: Evans, G., et al.
Published: (2014)

Defining the ABC of gene essentiality in streptococci
by: Charbonneau, Amelia R. L., et al.
Published: (2017)