Isolation and characterization of novel broad host range bacteriophages of Vibrio cholerae O1 from Bengal

Objectives: We have isolated a total of five newer cholera phages which are novel broad host range to incorporate with the existing phage typing schemes for an extended typing scheme. Materials and Methods: These newly isolated phages were well characterized including the electron micrograph. A tota...

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Main Authors: Sarkar, BanwarilalL, Sarkar, Sounak, Das, Mayukh, Bhowmick, TusharSuvra, Koley, Hemanta, Atterbury, Robert, Chakrabarti, AlokK
Format: Article
Published: Medknow Publications 2018
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Online Access:https://eprints.nottingham.ac.uk/52497/
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author Sarkar, BanwarilalL
Sarkar, Sounak
Das, Mayukh
Bhowmick, TusharSuvra
Koley, Hemanta
Atterbury, Robert
Chakrabarti, AlokK
author_facet Sarkar, BanwarilalL
Sarkar, Sounak
Das, Mayukh
Bhowmick, TusharSuvra
Koley, Hemanta
Atterbury, Robert
Chakrabarti, AlokK
author_sort Sarkar, BanwarilalL
building Nottingham Research Data Repository
collection Online Access
description Objectives: We have isolated a total of five newer cholera phages which are novel broad host range to incorporate with the existing phage typing schemes for an extended typing scheme. Materials and Methods: These newly isolated phages were well characterized including the electron micrograph. A total of 300 Vibrio cholerae strains were isolated from the different endemic region in India were included in phage typing study. Results: These phages were found different from the existing phages. Electron microscopic results showed that the phages belonged to myophage and podophage group. Characterization of the phages based on pH, temperature, and organic solvent sensitivity showed differences among the phages used in this study. All the strains of Vibrio O1 were typeable (100%) with the five set of cholera phages. Of these, 40% strains were clustered under Type-1. Conclusion: The newer Vibrio phages are novel and broad host range and will be useful to incorporate with the existing phage typing system for more precisely discriminate the strains of Vibrio cholerae.
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publishDate 2018
publisher Medknow Publications
recordtype eprints
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spelling nottingham-524972020-05-04T19:37:36Z https://eprints.nottingham.ac.uk/52497/ Isolation and characterization of novel broad host range bacteriophages of Vibrio cholerae O1 from Bengal Sarkar, BanwarilalL Sarkar, Sounak Das, Mayukh Bhowmick, TusharSuvra Koley, Hemanta Atterbury, Robert Chakrabarti, AlokK Objectives: We have isolated a total of five newer cholera phages which are novel broad host range to incorporate with the existing phage typing schemes for an extended typing scheme. Materials and Methods: These newly isolated phages were well characterized including the electron micrograph. A total of 300 Vibrio cholerae strains were isolated from the different endemic region in India were included in phage typing study. Results: These phages were found different from the existing phages. Electron microscopic results showed that the phages belonged to myophage and podophage group. Characterization of the phages based on pH, temperature, and organic solvent sensitivity showed differences among the phages used in this study. All the strains of Vibrio O1 were typeable (100%) with the five set of cholera phages. Of these, 40% strains were clustered under Type-1. Conclusion: The newer Vibrio phages are novel and broad host range and will be useful to incorporate with the existing phage typing system for more precisely discriminate the strains of Vibrio cholerae. Medknow Publications 2018-05-23 Article PeerReviewed Sarkar, BanwarilalL, Sarkar, Sounak, Das, Mayukh, Bhowmick, TusharSuvra, Koley, Hemanta, Atterbury, Robert and Chakrabarti, AlokK (2018) Isolation and characterization of novel broad host range bacteriophages of Vibrio cholerae O1 from Bengal. Journal of Global Infectious Diseases, 10 (2). pp. 84-88. ISSN 0974-8245 Bacteriophages isolation morphology phage typing plaque Vibrio cholerae http://dx.doi.org/10.4103/jgid.jgid_37_17 doi:10.4103/jgid.jgid_37_17 doi:10.4103/jgid.jgid_37_17
spellingShingle Bacteriophages
isolation
morphology
phage typing
plaque
Vibrio cholerae
Sarkar, BanwarilalL
Sarkar, Sounak
Das, Mayukh
Bhowmick, TusharSuvra
Koley, Hemanta
Atterbury, Robert
Chakrabarti, AlokK
Isolation and characterization of novel broad host range bacteriophages of Vibrio cholerae O1 from Bengal
title Isolation and characterization of novel broad host range bacteriophages of Vibrio cholerae O1 from Bengal
title_full Isolation and characterization of novel broad host range bacteriophages of Vibrio cholerae O1 from Bengal
title_fullStr Isolation and characterization of novel broad host range bacteriophages of Vibrio cholerae O1 from Bengal
title_full_unstemmed Isolation and characterization of novel broad host range bacteriophages of Vibrio cholerae O1 from Bengal
title_short Isolation and characterization of novel broad host range bacteriophages of Vibrio cholerae O1 from Bengal
title_sort isolation and characterization of novel broad host range bacteriophages of vibrio cholerae o1 from bengal
topic Bacteriophages
isolation
morphology
phage typing
plaque
Vibrio cholerae
url https://eprints.nottingham.ac.uk/52497/
https://eprints.nottingham.ac.uk/52497/
https://eprints.nottingham.ac.uk/52497/