Gallium incorporation into phosphate based glasses: bulk and thin film properties

The osteogenic ions Ca2+, P5+, Mg2+, and antimicrobial ion Ga3+ were homogenously dispersed into a 1.45 mum thick phosphate glass coating by plasma assisted sputtering onto CP grade titanium. The objective was to deliver therapeutic ions in orthopedic/dental implants such as hip prosthesis or dental...

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Main Authors: Stuart, Bryan W., Grant, Colin A., Stan, George E., Popa, Adrian C., Titman, Jeremy J., Grant, David M.
Format: Article
Published: Elsevier 2018
Subjects:
Online Access:https://eprints.nottingham.ac.uk/52417/
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author Stuart, Bryan W.
Grant, Colin A.
Stan, George E.
Popa, Adrian C.
Titman, Jeremy J.
Grant, David M.
author_facet Stuart, Bryan W.
Grant, Colin A.
Stan, George E.
Popa, Adrian C.
Titman, Jeremy J.
Grant, David M.
author_sort Stuart, Bryan W.
building Nottingham Research Data Repository
collection Online Access
description The osteogenic ions Ca2+, P5+, Mg2+, and antimicrobial ion Ga3+ were homogenously dispersed into a 1.45 mum thick phosphate glass coating by plasma assisted sputtering onto CP grade titanium. The objective was to deliver therapeutic ions in orthopedic/dental implants such as hip prosthesis or dental screws. The hardness 4.7 GPa and elastic modulus 69.7 GPa, of the coating were comparable to plasma sprayed hydroxyapatite/dental enamel, whilst superseding femoral cortical bone. To investigate the manufacturing challenge of translation from a target to vapour condensed coating, structural/compositional properties of the target (P51MQ) were compared to the coating (P40PVD) and a melt-quenched equivalent (P40MQ). Following condensation from P51MQ to P40PVD, P2O5 content reduced from 48.9 to 40.5 mol%. This depolymerisation and reduction in the P-O-P bridging oxygen content as determined by 31P-NMR, FTIR and Raman spectroscopy techniques was attributed to a decrease in the P2O5 network former and increases in alkali/alkali-earth cations. P40PVD appeared denser (3.47 vs. 2.70 g cm-3) and more polymerised than it’s compositionally equivalent P40MQ, showing that structure/ mechanical properties were affected by manufacturing route.
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spelling nottingham-524172020-05-04T19:44:17Z https://eprints.nottingham.ac.uk/52417/ Gallium incorporation into phosphate based glasses: bulk and thin film properties Stuart, Bryan W. Grant, Colin A. Stan, George E. Popa, Adrian C. Titman, Jeremy J. Grant, David M. The osteogenic ions Ca2+, P5+, Mg2+, and antimicrobial ion Ga3+ were homogenously dispersed into a 1.45 mum thick phosphate glass coating by plasma assisted sputtering onto CP grade titanium. The objective was to deliver therapeutic ions in orthopedic/dental implants such as hip prosthesis or dental screws. The hardness 4.7 GPa and elastic modulus 69.7 GPa, of the coating were comparable to plasma sprayed hydroxyapatite/dental enamel, whilst superseding femoral cortical bone. To investigate the manufacturing challenge of translation from a target to vapour condensed coating, structural/compositional properties of the target (P51MQ) were compared to the coating (P40PVD) and a melt-quenched equivalent (P40MQ). Following condensation from P51MQ to P40PVD, P2O5 content reduced from 48.9 to 40.5 mol%. This depolymerisation and reduction in the P-O-P bridging oxygen content as determined by 31P-NMR, FTIR and Raman spectroscopy techniques was attributed to a decrease in the P2O5 network former and increases in alkali/alkali-earth cations. P40PVD appeared denser (3.47 vs. 2.70 g cm-3) and more polymerised than it’s compositionally equivalent P40MQ, showing that structure/ mechanical properties were affected by manufacturing route. Elsevier 2018-06-30 Article PeerReviewed Stuart, Bryan W., Grant, Colin A., Stan, George E., Popa, Adrian C., Titman, Jeremy J. and Grant, David M. (2018) Gallium incorporation into phosphate based glasses: bulk and thin film properties. Journal of the Mechanical Behavior of Biomedical Materials, 82 . pp. 371-382. ISSN 1751-6161 Phosphate glass ; Sputtering ; Coating ; Osseointegration ; Antimicrobial https://www.sciencedirect.com/science/article/pii/S1751616118302856 doi:10.1016/j.jmbbm.2018.03.041 doi:10.1016/j.jmbbm.2018.03.041
spellingShingle Phosphate glass ; Sputtering ; Coating ; Osseointegration ; Antimicrobial
Stuart, Bryan W.
Grant, Colin A.
Stan, George E.
Popa, Adrian C.
Titman, Jeremy J.
Grant, David M.
Gallium incorporation into phosphate based glasses: bulk and thin film properties
title Gallium incorporation into phosphate based glasses: bulk and thin film properties
title_full Gallium incorporation into phosphate based glasses: bulk and thin film properties
title_fullStr Gallium incorporation into phosphate based glasses: bulk and thin film properties
title_full_unstemmed Gallium incorporation into phosphate based glasses: bulk and thin film properties
title_short Gallium incorporation into phosphate based glasses: bulk and thin film properties
title_sort gallium incorporation into phosphate based glasses: bulk and thin film properties
topic Phosphate glass ; Sputtering ; Coating ; Osseointegration ; Antimicrobial
url https://eprints.nottingham.ac.uk/52417/
https://eprints.nottingham.ac.uk/52417/
https://eprints.nottingham.ac.uk/52417/