The metabolic and molecular mechanisms of hyperammonaemia and hyperethanolaemia induced protein catabolism in skeletal muscle cells

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The metabolic and molecular mechanisms of hyperammonaemia and hyperethanolaemia induced protein catabolism in skeletal muscle cells

Hyperammonaemia and hyperethanolaemia are thought to be driving factors behind skeletal muscle myopathy in liver disease i.e. cirrhosis. Despite this, the singular and combined impacts of ethanol and ammonia induced protein catabolism are poorly defined. As such, we aimed to dissect out the effects...

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Bibliographic Details
Main Authors:	Crossland, Hannah, Smith, Kenneth, Atherton, Philip J., Wilkinson, Daniel J.
Format:	Article
Published:	Wiley 2018
Subjects:	Skeletal muscle; Protein catabolism; Hyper-ammonaemia
Online Access:	https://eprints.nottingham.ac.uk/52292/

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