Demonstration of differences in colonic volumes, transit, chyme consistency and response to psyllium between healthy and constipated subjects using magnetic resonance imaging

Demonstration of differences in colonic volumes, transit, chyme consistency and response to psyllium between healthy and constipated subjects using magnetic resonance imaging

Background: In functional gastrointestinal disorders a lack of objective biomarkers limits evaluation of underlying mechanisms. We aimed to demonstrate the utility of Magnetic Resonance Imaging (MRI) for this task using psyllium, an effective constipation treatment, in patients and controls. Met...

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Bibliographic Details
Main Authors: Major, Giles, Murray, Kathryn, Singh, Gulzar, Nowak, Adam, Hoad, Caroline L., Marciani, Luca, Silos-Santiago, ada, Kurtz, Caroline B., Johnston, Jeffrey, Gowland, Penny, Spiller, Robin C.
Format: Article
Published: Wiley 2018
Subjects:
ispaghula
laxative
relaxometry
MRI
Online Access:https://eprints.nottingham.ac.uk/52285/

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