Rapid one-step biotinylation of biological and non-biological surfaces

We describe a rapid one-step method to biotinylate virtually any biological or non-biological surface. Contacting a solution of biotin-spacer-lipid constructs with a surface will form a coating within seconds on non-biological surfaces or within minutes on most biological membranes including membran...

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Main Authors: Henry, Stephen, Williams, Eleanor, Barr, Katie, Korchagina, Elena, Tuzikov, Alexandr, Ilyushina, Natalia, Abayzeed, Sidahmed A., Webb, Kevin F., Bovin, Nicolai
Format: Article
Published: Nature Publishing Group 2018
Online Access:https://eprints.nottingham.ac.uk/52262/
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author Henry, Stephen
Williams, Eleanor
Barr, Katie
Korchagina, Elena
Tuzikov, Alexandr
Ilyushina, Natalia
Abayzeed, Sidahmed A.
Webb, Kevin F.
Bovin, Nicolai
author_facet Henry, Stephen
Williams, Eleanor
Barr, Katie
Korchagina, Elena
Tuzikov, Alexandr
Ilyushina, Natalia
Abayzeed, Sidahmed A.
Webb, Kevin F.
Bovin, Nicolai
author_sort Henry, Stephen
building Nottingham Research Data Repository
collection Online Access
description We describe a rapid one-step method to biotinylate virtually any biological or non-biological surface. Contacting a solution of biotin-spacer-lipid constructs with a surface will form a coating within seconds on non-biological surfaces or within minutes on most biological membranes including membrane viruses. The resultant biotinylated surface can then be used to interact with avidinylated conjugates, beads, vesicles, surfaces or cells.
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publishDate 2018
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spelling nottingham-522622020-05-04T19:31:51Z https://eprints.nottingham.ac.uk/52262/ Rapid one-step biotinylation of biological and non-biological surfaces Henry, Stephen Williams, Eleanor Barr, Katie Korchagina, Elena Tuzikov, Alexandr Ilyushina, Natalia Abayzeed, Sidahmed A. Webb, Kevin F. Bovin, Nicolai We describe a rapid one-step method to biotinylate virtually any biological or non-biological surface. Contacting a solution of biotin-spacer-lipid constructs with a surface will form a coating within seconds on non-biological surfaces or within minutes on most biological membranes including membrane viruses. The resultant biotinylated surface can then be used to interact with avidinylated conjugates, beads, vesicles, surfaces or cells. Nature Publishing Group 2018-02-12 Article PeerReviewed Henry, Stephen, Williams, Eleanor, Barr, Katie, Korchagina, Elena, Tuzikov, Alexandr, Ilyushina, Natalia, Abayzeed, Sidahmed A., Webb, Kevin F. and Bovin, Nicolai (2018) Rapid one-step biotinylation of biological and non-biological surfaces. Scientific Reports, 8 (1). 2845/1-2845/6. ISSN 2045-2322 https://doi.org/10.1038/s41598-018-21186-3 doi:10.1038/s41598-018-21186-3 doi:10.1038/s41598-018-21186-3
spellingShingle Henry, Stephen
Williams, Eleanor
Barr, Katie
Korchagina, Elena
Tuzikov, Alexandr
Ilyushina, Natalia
Abayzeed, Sidahmed A.
Webb, Kevin F.
Bovin, Nicolai
Rapid one-step biotinylation of biological and non-biological surfaces
title Rapid one-step biotinylation of biological and non-biological surfaces
title_full Rapid one-step biotinylation of biological and non-biological surfaces
title_fullStr Rapid one-step biotinylation of biological and non-biological surfaces
title_full_unstemmed Rapid one-step biotinylation of biological and non-biological surfaces
title_short Rapid one-step biotinylation of biological and non-biological surfaces
title_sort rapid one-step biotinylation of biological and non-biological surfaces
url https://eprints.nottingham.ac.uk/52262/
https://eprints.nottingham.ac.uk/52262/
https://eprints.nottingham.ac.uk/52262/