Metabolic therapy with PEG-arginase induces a sustained complete remission in immunotherapy-resistant melanoma
Background Metastatic melanoma is an aggressive skin cancer with a poor prognosis. Current treatment strategies for high-stage melanoma are based around the use of immunotherapy with immune checkpoint inhibitors such as anti-PDL1 or anti-CTLA4 antibodies to stimulate anti-cancer T cell responses,...
| Main Authors: | , , , , , |
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| Format: | Article |
| Published: |
BioMed Central
2018
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| Online Access: | https://eprints.nottingham.ac.uk/51989/ |