Manganese-enhanced magnetic resonance imaging depicts brain activity in models of acute and chronic pain: a new window to study experimental spontaneous pain?

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Manganese-enhanced magnetic resonance imaging depicts brain activity in models of acute and chronic pain: a new window to study experimental spontaneous pain?

Application of functional imaging techniques to animal models is vital to understand pain mechanisms, but is often confounded by the need to limit movement artefacts with anaesthesia, and a focus on evoked responses rather than clinically relevant spontaneous pain and related hyperalgesia. The aim o...

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Bibliographic Details
Main Authors:	Devonshire, Ian M., Burston, James, Xu, Luting, Lillywhite, A., Prior, M.J., Watson, David J.G., Greenspon, C.M., Iwabuchi, Sarina J., Auer, Dorothee P., Chapman, Victoria
Format:	Article
Published:	Elsevier 2017
Subjects:	Nociception; fMRI; Manganese; On-going pain; Osteoarthritis
Online Access:	https://eprints.nottingham.ac.uk/51958/

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