Anti-nociceptive and desensitizing effects of olvanil on capsaicin-induced thermal hyperalgesia in the rat

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Anti-nociceptive and desensitizing effects of olvanil on capsaicin-induced thermal hyperalgesia in the rat

Background: Olvanil (NE 19550) is a non-pungent synthetic analogue of capsaicin, the natural pungent ingredient of capsicum which activates the transient receptor potential vanilloid type-1 (TRPV1) channel and was developed as a potential analgesic compound. Olvanil has potent anti-hyperalgesic effe...

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Bibliographic Details
Main Authors:	Alsalem, Mohammad, Millns, Paul, Altarifi, Ahmad, El-Salem, Khalid, Chapman, Victoria, Kendall, David A.
Format:	Article
Published:	BioMed Central 2016
Subjects:	Transient receptor potential vanilloid type 1 Cannabinoid receptor 1 Pungency and pain
Online Access:	https://eprints.nottingham.ac.uk/51955/

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