Garlic and gaseous mediators
Garlic (Allium sativum) and allied plant species are rich sources of sulfur compounds. Major roles for garlic and its sulfur constituents include the regulation of vascular homeostasis and the control of metabolic systems linked to nutrient metabolism. Recent studies have indicated that some of thes...
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| Format: | Article |
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Elsevier
2018
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| Online Access: | https://eprints.nottingham.ac.uk/51946/ |
| _version_ | 1848798610266783744 |
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| author | Rose, Peter Moore, Philip Keith Zhu, Yi-Zhun |
| author_facet | Rose, Peter Moore, Philip Keith Zhu, Yi-Zhun |
| author_sort | Rose, Peter |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Garlic (Allium sativum) and allied plant species are rich sources of sulfur compounds. Major roles for garlic and its sulfur constituents include the regulation of vascular homeostasis and the control of metabolic systems linked to nutrient metabolism. Recent studies have indicated that some of these sulfur compounds, such as diallyl trisulfide (DATS), alter the levels of gaseous signalling molecules including nitric oxide (NO), hydrogen sulfide (H2S), and perhaps carbon monoxide (CO) in mammalian tissues. These gases are important in cellular processes associated with the cardiovascular system, inflammation, and neurological functions. Importantly, these studies build on the known biological effects of garlic and associated sulfur constituents. This review highlights our current understanding of the health benefits attributed to edible plants like garlic. |
| first_indexed | 2025-11-14T20:22:30Z |
| format | Article |
| id | nottingham-51946 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T20:22:30Z |
| publishDate | 2018 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-519462020-05-04T19:33:44Z https://eprints.nottingham.ac.uk/51946/ Garlic and gaseous mediators Rose, Peter Moore, Philip Keith Zhu, Yi-Zhun Garlic (Allium sativum) and allied plant species are rich sources of sulfur compounds. Major roles for garlic and its sulfur constituents include the regulation of vascular homeostasis and the control of metabolic systems linked to nutrient metabolism. Recent studies have indicated that some of these sulfur compounds, such as diallyl trisulfide (DATS), alter the levels of gaseous signalling molecules including nitric oxide (NO), hydrogen sulfide (H2S), and perhaps carbon monoxide (CO) in mammalian tissues. These gases are important in cellular processes associated with the cardiovascular system, inflammation, and neurological functions. Importantly, these studies build on the known biological effects of garlic and associated sulfur constituents. This review highlights our current understanding of the health benefits attributed to edible plants like garlic. Elsevier 2018-04-26 Article PeerReviewed Rose, Peter, Moore, Philip Keith and Zhu, Yi-Zhun (2018) Garlic and gaseous mediators. Trends in Pharmacological Sciences . ISSN 1873-3735 Hydrogen sulfide; Nitric oxide; Carbon monoxide; Gaseous mediators; Garlic; Polysulfide https://doi.org/10.1016/j.tips.2018.03.009 doi:10.1016/j.tips.2018.03.009 doi:10.1016/j.tips.2018.03.009 |
| spellingShingle | Hydrogen sulfide; Nitric oxide; Carbon monoxide; Gaseous mediators; Garlic; Polysulfide Rose, Peter Moore, Philip Keith Zhu, Yi-Zhun Garlic and gaseous mediators |
| title | Garlic and gaseous mediators |
| title_full | Garlic and gaseous mediators |
| title_fullStr | Garlic and gaseous mediators |
| title_full_unstemmed | Garlic and gaseous mediators |
| title_short | Garlic and gaseous mediators |
| title_sort | garlic and gaseous mediators |
| topic | Hydrogen sulfide; Nitric oxide; Carbon monoxide; Gaseous mediators; Garlic; Polysulfide |
| url | https://eprints.nottingham.ac.uk/51946/ https://eprints.nottingham.ac.uk/51946/ https://eprints.nottingham.ac.uk/51946/ |