Following acute encephalitis, Semliki Forest virus is undetectable in the brain by infectivity assays but functional virus RNA capable of generating infectious virus persists for life

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Following acute encephalitis, Semliki Forest virus is undetectable in the brain by infectivity assays but functional virus RNA capable of generating infectious virus persists for life

Alphaviruses are mosquito-transmitted RNA viruses which generally cause acute disease including mild febrile illness, rash, arthralgia, myalgia and more severely, encephalitis. In the mouse, peripheral infection with Semliki Forest virus (SFV) results in encephalitis. With non-virulent strains, infe...

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Bibliographic Details
Main Authors:	Fragkoudis, Rennos, Dixon-Ballany, Catherine, Zagrajek, Adrian, Kedzierski, Lukasz, Fazakerley, John
Format:	Article
Published:	MDPI 2018
Subjects:	Semliki Forest virus; alphavirus; persistence
Online Access:	https://eprints.nottingham.ac.uk/51945/

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