Engineering of a thermostable alcohol dehydrogenase towards imine reduction

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Engineering of a thermostable alcohol dehydrogenase towards imine reduction

The enantioselective reduction of carbon-nitrogen double bonds is a powerful tool for accessing chiral secondary amines. These are important building blocks in the production of many high-added value chemicals, with an estimated 40-45 % of all pharmaceuticals and 20 % of agrochemicals containing a c...

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Bibliographic Details
Main Author:	Nethercott, Alanna Mary
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2018
Subjects:	Chiral secondary amines; Imines; Imine reductases; Biocatalysis; Alcohol dehydrogenase
Online Access:	https://eprints.nottingham.ac.uk/51890/

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