Systematic review of the evidence for sustained efficacy of dietary interventions for reducing appetite or energy intake
We assessed evidence for changes in efficacy of food-based interventions aimed at reducing appetite or energy intake (EI), and whether this could be used to provide guidance on trial design. A systematic search identified randomized controlled trials testing sustained efficacy of diets, foods, sup...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
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Wiley
2018
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| Online Access: | https://eprints.nottingham.ac.uk/51889/ |
| _version_ | 1848798597143855104 |
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| author | Halford, Jason C.G. Masic, Una Marseaux, Cyril F.M. Jones, Andrew J. Lluch, Anne Marciani, Luca Mars, Monica Vinoy, Sophie Westerterp-Plantenga, Margriet Mela, David J. |
| author_facet | Halford, Jason C.G. Masic, Una Marseaux, Cyril F.M. Jones, Andrew J. Lluch, Anne Marciani, Luca Mars, Monica Vinoy, Sophie Westerterp-Plantenga, Margriet Mela, David J. |
| author_sort | Halford, Jason C.G. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | We assessed evidence for changes in efficacy of food-based interventions aimed at reducing appetite or energy intake (EI), and whether this could be used to provide guidance on trial design.
A systematic search identified randomized controlled trials testing sustained efficacy of diets, foods, supplements or food ingredients on appetite and/or EI. Trials had to include sufficient exposure duration (≥3 days) with appetite and/or EI measured after both acute and repeated exposures.
Twenty-six trials met the inclusion criteria and reported data allowing for assessment of the acute and chronic effects of interventions. Most (21/26) measured appetite outcomes and over half (14/26) had objective measures of EI. A significant acute effect of the intervention was retained in 10 of 12 trials for appetite outcomes, and six of nine studies for EI. Initial effects were most likely retained where these were more robust and studies adequately powered. Where the initial, acute effect was not statistically significant, a significant effect was later observed in only two of nine studies for appetite and none of five studies for EI.
Maintenance of intervention effects on appetite or EI needs to be confirmed, but seem likely where acute effects are robust and replicable in adequately powered studies. |
| first_indexed | 2025-11-14T20:22:18Z |
| format | Article |
| id | nottingham-51889 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T20:22:18Z |
| publishDate | 2018 |
| publisher | Wiley |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-518892020-05-04T19:42:15Z https://eprints.nottingham.ac.uk/51889/ Systematic review of the evidence for sustained efficacy of dietary interventions for reducing appetite or energy intake Halford, Jason C.G. Masic, Una Marseaux, Cyril F.M. Jones, Andrew J. Lluch, Anne Marciani, Luca Mars, Monica Vinoy, Sophie Westerterp-Plantenga, Margriet Mela, David J. We assessed evidence for changes in efficacy of food-based interventions aimed at reducing appetite or energy intake (EI), and whether this could be used to provide guidance on trial design. A systematic search identified randomized controlled trials testing sustained efficacy of diets, foods, supplements or food ingredients on appetite and/or EI. Trials had to include sufficient exposure duration (≥3 days) with appetite and/or EI measured after both acute and repeated exposures. Twenty-six trials met the inclusion criteria and reported data allowing for assessment of the acute and chronic effects of interventions. Most (21/26) measured appetite outcomes and over half (14/26) had objective measures of EI. A significant acute effect of the intervention was retained in 10 of 12 trials for appetite outcomes, and six of nine studies for EI. Initial effects were most likely retained where these were more robust and studies adequately powered. Where the initial, acute effect was not statistically significant, a significant effect was later observed in only two of nine studies for appetite and none of five studies for EI. Maintenance of intervention effects on appetite or EI needs to be confirmed, but seem likely where acute effects are robust and replicable in adequately powered studies. Wiley 2018-06-25 Article PeerReviewed Halford, Jason C.G., Masic, Una, Marseaux, Cyril F.M., Jones, Andrew J., Lluch, Anne, Marciani, Luca, Mars, Monica, Vinoy, Sophie, Westerterp-Plantenga, Margriet and Mela, David J. (2018) Systematic review of the evidence for sustained efficacy of dietary interventions for reducing appetite or energy intake. Obesity Reviews . ISSN 1467-789X Study duration Satiety Energy intake Appetite https://onlinelibrary.wiley.com/doi/full/10.1111/obr.12712 doi:10.1111/obr.12712 doi:10.1111/obr.12712 |
| spellingShingle | Study duration Satiety Energy intake Appetite Halford, Jason C.G. Masic, Una Marseaux, Cyril F.M. Jones, Andrew J. Lluch, Anne Marciani, Luca Mars, Monica Vinoy, Sophie Westerterp-Plantenga, Margriet Mela, David J. Systematic review of the evidence for sustained efficacy of dietary interventions for reducing appetite or energy intake |
| title | Systematic review of the evidence for sustained efficacy of dietary interventions for reducing appetite or energy intake |
| title_full | Systematic review of the evidence for sustained efficacy of dietary interventions for reducing appetite or energy intake |
| title_fullStr | Systematic review of the evidence for sustained efficacy of dietary interventions for reducing appetite or energy intake |
| title_full_unstemmed | Systematic review of the evidence for sustained efficacy of dietary interventions for reducing appetite or energy intake |
| title_short | Systematic review of the evidence for sustained efficacy of dietary interventions for reducing appetite or energy intake |
| title_sort | systematic review of the evidence for sustained efficacy of dietary interventions for reducing appetite or energy intake |
| topic | Study duration Satiety Energy intake Appetite |
| url | https://eprints.nottingham.ac.uk/51889/ https://eprints.nottingham.ac.uk/51889/ https://eprints.nottingham.ac.uk/51889/ |