Transcriptomic gene signatures associated with persistent airflow limitation in patients with severe asthma
A proportion of severe asthma patients suffers from persistent airflow limitation (PAL), often associated with more symptoms and exacerbations. Little is known about the underlying mechanisms. Here, our aim was to discover unexplored potential mechanisms using Gene Set Variation Analysis (GSVA), a s...
| Main Authors: | Hekking, Pieter-Paul, Loza, Matthew J., Pavlidis, Stelios, De Meulder, Bertrand, Lefaudeux, Diane, Baribaud, Frederic, Auffray, Charles, Wagener, Ariane H., Brinkman, Paul, Lutter, René, Bansal, Aruna T., Sousa, Ana R., Bates, Stewart A., Pandis, Ioannis, Fleming, Louise J., Shaw, Dominick E., Fowler, Stephen J., Guo, Yike, Meiser, Andrea, Sun, Kai, Corfield, Julie, Howarth, Peter, Bel, Elisabeth H., Adcock, Ian M., Chung, Kian Fan, Djukanovic, Ratko, Sterk, Peter J. |
|---|---|
| Format: | Article |
| Published: |
European Respiratory Society
2017
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| Online Access: | https://eprints.nottingham.ac.uk/51852/ |
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