Exercise and other nonpharmacological strategies to reduce blood pressure in older adults: a systematic review and meta-analysis

The incidence of hypertension increases with advancing age and represents a significant burden of disease. Lifestyle modification represents the first-line intervention in treatment algorithms; however, the majority of evidence for this comes from studies involving young participants using intervent...

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Main Authors: Herrod, Philip J.J., Doleman, Brett, Blackwell, James E.M., O’Boyle, Francesca, Williams, John P., Lund, Jonathan N., Phillips, Bethan E.
Format: Article
Published: Elsevier 2018
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Online Access:https://eprints.nottingham.ac.uk/51792/
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author Herrod, Philip J.J.
Doleman, Brett
Blackwell, James E.M.
O’Boyle, Francesca
Williams, John P.
Lund, Jonathan N.
Phillips, Bethan E.
author_facet Herrod, Philip J.J.
Doleman, Brett
Blackwell, James E.M.
O’Boyle, Francesca
Williams, John P.
Lund, Jonathan N.
Phillips, Bethan E.
author_sort Herrod, Philip J.J.
building Nottingham Research Data Repository
collection Online Access
description The incidence of hypertension increases with advancing age and represents a significant burden of disease. Lifestyle modification represents the first-line intervention in treatment algorithms; however, the majority of evidence for this comes from studies involving young participants using interventions that may not always be feasible in the elderly. This manuscript presents a systematic review of all randomized controlled trials involving participants with a mean age of 65 or over investigating nonpharmacological strategies to reduce blood pressure (BP). Fifty-three randomized controlled trials were included. The majority of interventions described aerobic exercise training, dynamic resistance exercise training, or combined aerobic and dynamic resistance exercise training (COM), with limited studies reporting isometric exercise training or alternative lifestyle strategies. Aerobic exercise training, dynamic resistance exercise training, COM, and isometric exercise training all elicited significant reductions in both systolic and diastolic BP, with no additional benefit of COM compared with single modality exercise training. Three months of traditional exercise-based lifestyle intervention may produce a reduction in BP of approximately 5 mmHg systolic and 3 mmHg diastolic in older individuals, similar to that expected in younger individuals.
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spelling nottingham-517922020-05-04T19:29:40Z https://eprints.nottingham.ac.uk/51792/ Exercise and other nonpharmacological strategies to reduce blood pressure in older adults: a systematic review and meta-analysis Herrod, Philip J.J. Doleman, Brett Blackwell, James E.M. O’Boyle, Francesca Williams, John P. Lund, Jonathan N. Phillips, Bethan E. The incidence of hypertension increases with advancing age and represents a significant burden of disease. Lifestyle modification represents the first-line intervention in treatment algorithms; however, the majority of evidence for this comes from studies involving young participants using interventions that may not always be feasible in the elderly. This manuscript presents a systematic review of all randomized controlled trials involving participants with a mean age of 65 or over investigating nonpharmacological strategies to reduce blood pressure (BP). Fifty-three randomized controlled trials were included. The majority of interventions described aerobic exercise training, dynamic resistance exercise training, or combined aerobic and dynamic resistance exercise training (COM), with limited studies reporting isometric exercise training or alternative lifestyle strategies. Aerobic exercise training, dynamic resistance exercise training, COM, and isometric exercise training all elicited significant reductions in both systolic and diastolic BP, with no additional benefit of COM compared with single modality exercise training. Three months of traditional exercise-based lifestyle intervention may produce a reduction in BP of approximately 5 mmHg systolic and 3 mmHg diastolic in older individuals, similar to that expected in younger individuals. Elsevier 2018-02-02 Article PeerReviewed Herrod, Philip J.J., Doleman, Brett, Blackwell, James E.M., O’Boyle, Francesca, Williams, John P., Lund, Jonathan N. and Phillips, Bethan E. (2018) Exercise and other nonpharmacological strategies to reduce blood pressure in older adults: a systematic review and meta-analysis. Journal of the American Society of Hypertension, 12 (4). pp. 248-267. ISSN 1878-7436 Elderly; hypertension; non-drug https://www.sciencedirect.com/science/article/pii/S1933171118300093?via%3Dihub doi:10.1016/j.jash.2018.01.008 doi:10.1016/j.jash.2018.01.008
spellingShingle Elderly; hypertension; non-drug
Herrod, Philip J.J.
Doleman, Brett
Blackwell, James E.M.
O’Boyle, Francesca
Williams, John P.
Lund, Jonathan N.
Phillips, Bethan E.
Exercise and other nonpharmacological strategies to reduce blood pressure in older adults: a systematic review and meta-analysis
title Exercise and other nonpharmacological strategies to reduce blood pressure in older adults: a systematic review and meta-analysis
title_full Exercise and other nonpharmacological strategies to reduce blood pressure in older adults: a systematic review and meta-analysis
title_fullStr Exercise and other nonpharmacological strategies to reduce blood pressure in older adults: a systematic review and meta-analysis
title_full_unstemmed Exercise and other nonpharmacological strategies to reduce blood pressure in older adults: a systematic review and meta-analysis
title_short Exercise and other nonpharmacological strategies to reduce blood pressure in older adults: a systematic review and meta-analysis
title_sort exercise and other nonpharmacological strategies to reduce blood pressure in older adults: a systematic review and meta-analysis
topic Elderly; hypertension; non-drug
url https://eprints.nottingham.ac.uk/51792/
https://eprints.nottingham.ac.uk/51792/
https://eprints.nottingham.ac.uk/51792/