Post infectious IBS: defining its clinical features and prognosis using an internet-based survey
Background: Gastrointestinal infection is an important risk factor for developing IBS. Our aim was to characterise postinfectious IBS (PI-IBS) compared to other IBS patients. Methods: An internet survey of IBS patients using Rome III diagnostic questionnaire, Hospital Anxiety & Depression Scale...
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| Format: | Article |
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SAGE
2018
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| Online Access: | https://eprints.nottingham.ac.uk/51696/ |
| _version_ | 1848798553792577536 |
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| author | Card, Timothy Enck, Paul Barbara, Giovanni Boeckxstaens, Guy E.E Santos, Javier Azpiroz, Fernando Mearin, Fermin Aziz, Qasim Marshall, John Spiller, Robin C. |
| author_facet | Card, Timothy Enck, Paul Barbara, Giovanni Boeckxstaens, Guy E.E Santos, Javier Azpiroz, Fernando Mearin, Fermin Aziz, Qasim Marshall, John Spiller, Robin C. |
| author_sort | Card, Timothy |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Background: Gastrointestinal infection is an important risk factor for developing IBS. Our aim was to characterise postinfectious IBS (PI-IBS) compared to other IBS patients.
Methods: An internet survey of IBS patients using Rome III diagnostic questionnaire, Hospital Anxiety & Depression Scale (HADS) and Patient Health Questionnaire-12 somatic symptom score (PHQ12-SS) documenting the mode of onset.
Results: 7811 participants, 63.2% female of whom 1004 (13.3%) met criteria for PI-IBS. 70% of PI-IBS described sudden onset, 35% onset while travelling, 49.6% vomiting, 49.9 fever and 20.3% bloody diarrhoea. Compared to other IBS, PI-IBS was significantly associated with living in Northern Europe and North America, having a hysterectomy, not having an appendectomy, higher PHQ12-SS score and having more than one toilet in the family home. PI-IBS patients had more frequent stools. At 1 year recovery rate in PI-IBS and non-PI-IBS group was 19.7% and 22.2%, p=0.15. Recovery rates were lower for females (20.7%) versus males (38.8%), those with somatisation ( 23.0%) versus those without (33.2%) and living in North America or Northern Europe (21.1%) versus living elsewhere (33.9%) p=<0.001.
Conclusion: PI-IBS accounts for around 13% of all IBS in this internet sample, with some distinctive features but a similar prognosis to the remainder. |
| first_indexed | 2025-11-14T20:21:36Z |
| format | Article |
| id | nottingham-51696 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T20:21:36Z |
| publishDate | 2018 |
| publisher | SAGE |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-516962024-08-15T15:29:00Z https://eprints.nottingham.ac.uk/51696/ Post infectious IBS: defining its clinical features and prognosis using an internet-based survey Card, Timothy Enck, Paul Barbara, Giovanni Boeckxstaens, Guy E.E Santos, Javier Azpiroz, Fernando Mearin, Fermin Aziz, Qasim Marshall, John Spiller, Robin C. Background: Gastrointestinal infection is an important risk factor for developing IBS. Our aim was to characterise postinfectious IBS (PI-IBS) compared to other IBS patients. Methods: An internet survey of IBS patients using Rome III diagnostic questionnaire, Hospital Anxiety & Depression Scale (HADS) and Patient Health Questionnaire-12 somatic symptom score (PHQ12-SS) documenting the mode of onset. Results: 7811 participants, 63.2% female of whom 1004 (13.3%) met criteria for PI-IBS. 70% of PI-IBS described sudden onset, 35% onset while travelling, 49.6% vomiting, 49.9 fever and 20.3% bloody diarrhoea. Compared to other IBS, PI-IBS was significantly associated with living in Northern Europe and North America, having a hysterectomy, not having an appendectomy, higher PHQ12-SS score and having more than one toilet in the family home. PI-IBS patients had more frequent stools. At 1 year recovery rate in PI-IBS and non-PI-IBS group was 19.7% and 22.2%, p=0.15. Recovery rates were lower for females (20.7%) versus males (38.8%), those with somatisation ( 23.0%) versus those without (33.2%) and living in North America or Northern Europe (21.1%) versus living elsewhere (33.9%) p=<0.001. Conclusion: PI-IBS accounts for around 13% of all IBS in this internet sample, with some distinctive features but a similar prognosis to the remainder. SAGE 2018-05-23 Article PeerReviewed Card, Timothy, Enck, Paul, Barbara, Giovanni, Boeckxstaens, Guy E.E, Santos, Javier, Azpiroz, Fernando, Mearin, Fermin, Aziz, Qasim, Marshall, John and Spiller, Robin C. (2018) Post infectious IBS: defining its clinical features and prognosis using an internet-based survey. United European Gastroenterology Journal . ISSN 2050-6414 Infection Irritable bowel syndrome Survey Multinational Diarrhoea http://journals.sagepub.com/doi/10.1177/2050640618779923 doi:10.1177/2050640618779923 doi:10.1177/2050640618779923 |
| spellingShingle | Infection Irritable bowel syndrome Survey Multinational Diarrhoea Card, Timothy Enck, Paul Barbara, Giovanni Boeckxstaens, Guy E.E Santos, Javier Azpiroz, Fernando Mearin, Fermin Aziz, Qasim Marshall, John Spiller, Robin C. Post infectious IBS: defining its clinical features and prognosis using an internet-based survey |
| title | Post infectious IBS: defining its clinical features and prognosis using an internet-based survey |
| title_full | Post infectious IBS: defining its clinical features and prognosis using an internet-based survey |
| title_fullStr | Post infectious IBS: defining its clinical features and prognosis using an internet-based survey |
| title_full_unstemmed | Post infectious IBS: defining its clinical features and prognosis using an internet-based survey |
| title_short | Post infectious IBS: defining its clinical features and prognosis using an internet-based survey |
| title_sort | post infectious ibs: defining its clinical features and prognosis using an internet-based survey |
| topic | Infection Irritable bowel syndrome Survey Multinational Diarrhoea |
| url | https://eprints.nottingham.ac.uk/51696/ https://eprints.nottingham.ac.uk/51696/ https://eprints.nottingham.ac.uk/51696/ |