Estimation and prediction of avoidable health care costs of cardiovascular diseases and type 2 diabetes through adequate dairy food consumption: a systematic review and micro simulation modeling study
Background: Recent evidence from prospective cohort studies show a relationship between consumption of dairy foods and cardiovascular diseases (CVDs) and type 2 diabetes mellitus (T2DM). This association highlights the importance of dairy foods consumption in prevention of these diseases and also re...
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Academy of Medical Sciences
2018
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| Online Access: | https://eprints.nottingham.ac.uk/51612/ |
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| author | Javanbakht, Mehdi Jamshidi, Ahmad Reza Baradaran, Hamid Reza Mohammadi, Zahra Mashayekhi, Atefeh Shokraneh, Farhad Hamami, Mohsen Rezai Bakhsh, Raziyeh Yazdani Shabaninejad, Hossein Delavari, Sajad Tehrani, Arash |
| author_facet | Javanbakht, Mehdi Jamshidi, Ahmad Reza Baradaran, Hamid Reza Mohammadi, Zahra Mashayekhi, Atefeh Shokraneh, Farhad Hamami, Mohsen Rezai Bakhsh, Raziyeh Yazdani Shabaninejad, Hossein Delavari, Sajad Tehrani, Arash |
| author_sort | Javanbakht, Mehdi |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Background: Recent evidence from prospective cohort studies show a relationship between consumption of dairy foods and cardiovascular diseases (CVDs) and type 2 diabetes mellitus (T2DM). This association highlights the importance of dairy foods consumption in prevention of these diseases and also reduction of associated healthcare costs. The aim of this study was to estimate avoidable healthcare costs of CVD and T2D through adequate dairy foods consumption in Iran.
Methods: This was a multistage modelling study. We conducted a systematic literature review in PubMed and EMBASE to identify any association between incidence of CVD and T2DM and dairy foods intake, and also associated relative risks. We obtained age- and sex-specific dairy foods consumption level and healthcare expenditures from national surveys and studies. Patient level simulation Markov models were constructed to predict the disease incidence, patient population size and associated healthcare costs for current and optimal dairy foods consumption at different time horizons (1, 5, 10 and 20 years). All parameters including costs and transition probabilities were defined as statistical distributions in the models, and all analyses were conducted by accounting for first and second order uncertainty.
Results: The systematic review results indicated that dairy foods consumption was inversely associated with incidence of T2DM, coronary heart disease (CHD) and stroke. We estimated that the introduction of a diet containing 3 servings of dairy foods per day may produce a $0.43 saving in annual per capita healthcare costs in Iran in the first year due to saving in cost of CVD and T2DM treatment. The estimated savings in per capita healthcare costs were $8.42, $39.97 and $190.25 in 5, 10 and 20-years’ time, respectively. Corresponding total aggregated avoidable costs for the entire Iranian population within the study time horizons were $33.83, $661.31, $3,138.21 and $14,934.63 million, respectively.
Conclusion: Our analysis demonstrated that increasing dairy foods consumption to recommended levels would be associated with reductions in healthcare costs. Further randomized trial studies are required to investigate the effect of dairy foods intake on cost of CVD and T2DM in the population. |
| first_indexed | 2025-11-14T20:21:16Z |
| format | Article |
| id | nottingham-51612 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T20:21:16Z |
| publishDate | 2018 |
| publisher | Academy of Medical Sciences |
| recordtype | eprints |
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| spelling | nottingham-516122020-05-04T19:35:20Z https://eprints.nottingham.ac.uk/51612/ Estimation and prediction of avoidable health care costs of cardiovascular diseases and type 2 diabetes through adequate dairy food consumption: a systematic review and micro simulation modeling study Javanbakht, Mehdi Jamshidi, Ahmad Reza Baradaran, Hamid Reza Mohammadi, Zahra Mashayekhi, Atefeh Shokraneh, Farhad Hamami, Mohsen Rezai Bakhsh, Raziyeh Yazdani Shabaninejad, Hossein Delavari, Sajad Tehrani, Arash Background: Recent evidence from prospective cohort studies show a relationship between consumption of dairy foods and cardiovascular diseases (CVDs) and type 2 diabetes mellitus (T2DM). This association highlights the importance of dairy foods consumption in prevention of these diseases and also reduction of associated healthcare costs. The aim of this study was to estimate avoidable healthcare costs of CVD and T2D through adequate dairy foods consumption in Iran. Methods: This was a multistage modelling study. We conducted a systematic literature review in PubMed and EMBASE to identify any association between incidence of CVD and T2DM and dairy foods intake, and also associated relative risks. We obtained age- and sex-specific dairy foods consumption level and healthcare expenditures from national surveys and studies. Patient level simulation Markov models were constructed to predict the disease incidence, patient population size and associated healthcare costs for current and optimal dairy foods consumption at different time horizons (1, 5, 10 and 20 years). All parameters including costs and transition probabilities were defined as statistical distributions in the models, and all analyses were conducted by accounting for first and second order uncertainty. Results: The systematic review results indicated that dairy foods consumption was inversely associated with incidence of T2DM, coronary heart disease (CHD) and stroke. We estimated that the introduction of a diet containing 3 servings of dairy foods per day may produce a $0.43 saving in annual per capita healthcare costs in Iran in the first year due to saving in cost of CVD and T2DM treatment. The estimated savings in per capita healthcare costs were $8.42, $39.97 and $190.25 in 5, 10 and 20-years’ time, respectively. Corresponding total aggregated avoidable costs for the entire Iranian population within the study time horizons were $33.83, $661.31, $3,138.21 and $14,934.63 million, respectively. Conclusion: Our analysis demonstrated that increasing dairy foods consumption to recommended levels would be associated with reductions in healthcare costs. Further randomized trial studies are required to investigate the effect of dairy foods intake on cost of CVD and T2DM in the population. Academy of Medical Sciences 2018-05-01 Article PeerReviewed Javanbakht, Mehdi, Jamshidi, Ahmad Reza, Baradaran, Hamid Reza, Mohammadi, Zahra, Mashayekhi, Atefeh, Shokraneh, Farhad, Hamami, Mohsen Rezai, Bakhsh, Raziyeh Yazdani, Shabaninejad, Hossein, Delavari, Sajad and Tehrani, Arash (2018) Estimation and prediction of avoidable health care costs of cardiovascular diseases and type 2 diabetes through adequate dairy food consumption: a systematic review and micro simulation modeling study. Archives of Iranian Medicine, 21 (5). pp. 213-222. ISSN 1735-3947 Avoidable cost; Cardiovascular diseases; Dairy foods; Diabetes; Iran; Markov model http://www.aimjournal.ir/Abstract/aim-2180 |
| spellingShingle | Avoidable cost; Cardiovascular diseases; Dairy foods; Diabetes; Iran; Markov model Javanbakht, Mehdi Jamshidi, Ahmad Reza Baradaran, Hamid Reza Mohammadi, Zahra Mashayekhi, Atefeh Shokraneh, Farhad Hamami, Mohsen Rezai Bakhsh, Raziyeh Yazdani Shabaninejad, Hossein Delavari, Sajad Tehrani, Arash Estimation and prediction of avoidable health care costs of cardiovascular diseases and type 2 diabetes through adequate dairy food consumption: a systematic review and micro simulation modeling study |
| title | Estimation and prediction of avoidable health care costs of cardiovascular diseases and type 2 diabetes through adequate dairy food consumption: a systematic review and micro simulation modeling study |
| title_full | Estimation and prediction of avoidable health care costs of cardiovascular diseases and type 2 diabetes through adequate dairy food consumption: a systematic review and micro simulation modeling study |
| title_fullStr | Estimation and prediction of avoidable health care costs of cardiovascular diseases and type 2 diabetes through adequate dairy food consumption: a systematic review and micro simulation modeling study |
| title_full_unstemmed | Estimation and prediction of avoidable health care costs of cardiovascular diseases and type 2 diabetes through adequate dairy food consumption: a systematic review and micro simulation modeling study |
| title_short | Estimation and prediction of avoidable health care costs of cardiovascular diseases and type 2 diabetes through adequate dairy food consumption: a systematic review and micro simulation modeling study |
| title_sort | estimation and prediction of avoidable health care costs of cardiovascular diseases and type 2 diabetes through adequate dairy food consumption: a systematic review and micro simulation modeling study |
| topic | Avoidable cost; Cardiovascular diseases; Dairy foods; Diabetes; Iran; Markov model |
| url | https://eprints.nottingham.ac.uk/51612/ https://eprints.nottingham.ac.uk/51612/ |