Structure-function relationship of DEF6

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Structure-function relationship of DEF6

DEF6 (Differentially Expressed in FDCP 6, also known as IBP and SLAT) is critical for the development of autoimmune disease and cancer. In T cells, DEF6 participates in TCR-mediated signalling determining T helper cell-mediated immune responses. In addition, DEF6 acts as a guanine nucleotide exchang...

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Bibliographic Details
Main Author:	Cheng, Huaitao
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2018
Online Access:	https://eprints.nottingham.ac.uk/51561/

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