Nucleoside based self-assembling drugs for localized drug delivery
We have synthesized a range of gelators based on nucleoside analogues gemcitabine and lamivudine, characterizing representative gels from the series using rheology and TEM. Growth inhibition studies of gemcitabine derivatives confirmed the feasibility of these compounds as novel treatments, indicati...
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| Format: | Article |
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Wiley-VCH Verlag
2018
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| Online Access: | https://eprints.nottingham.ac.uk/51547/ |
| _version_ | 1848798520884068352 |
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| author | Skilling, Kathryn J. Stocks, Michael J. Kellam, Barrie Ashford, Marianne Bradshaw, Tracey Burroughs, Laurence Marlow, Maria |
| author_facet | Skilling, Kathryn J. Stocks, Michael J. Kellam, Barrie Ashford, Marianne Bradshaw, Tracey Burroughs, Laurence Marlow, Maria |
| author_sort | Skilling, Kathryn J. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | We have synthesized a range of gelators based on nucleoside analogues gemcitabine and lamivudine, characterizing representative gels from the series using rheology and TEM. Growth inhibition studies of gemcitabine derivatives confirmed the feasibility of these compounds as novel treatments, indicating the potential of nucleoside based gelators for localized drug delivery. |
| first_indexed | 2025-11-14T20:21:05Z |
| format | Article |
| id | nottingham-51547 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T20:21:05Z |
| publishDate | 2018 |
| publisher | Wiley-VCH Verlag |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-515472020-05-04T19:35:03Z https://eprints.nottingham.ac.uk/51547/ Nucleoside based self-assembling drugs for localized drug delivery Skilling, Kathryn J. Stocks, Michael J. Kellam, Barrie Ashford, Marianne Bradshaw, Tracey Burroughs, Laurence Marlow, Maria We have synthesized a range of gelators based on nucleoside analogues gemcitabine and lamivudine, characterizing representative gels from the series using rheology and TEM. Growth inhibition studies of gemcitabine derivatives confirmed the feasibility of these compounds as novel treatments, indicating the potential of nucleoside based gelators for localized drug delivery. Wiley-VCH Verlag 2018-05-02 Article PeerReviewed Skilling, Kathryn J., Stocks, Michael J., Kellam, Barrie, Ashford, Marianne, Bradshaw, Tracey, Burroughs, Laurence and Marlow, Maria (2018) Nucleoside based self-assembling drugs for localized drug delivery. ChemMedChem . ISSN 1860-7179 drug delivery ; gels ; gemcitabine ; lamivudine ; nucleosides https://onlinelibrary.wiley.com/doi/abs/10.1002/cmdc.201800063 doi:10.1002/cmdc.201800063 doi:10.1002/cmdc.201800063 |
| spellingShingle | drug delivery ; gels ; gemcitabine ; lamivudine ; nucleosides Skilling, Kathryn J. Stocks, Michael J. Kellam, Barrie Ashford, Marianne Bradshaw, Tracey Burroughs, Laurence Marlow, Maria Nucleoside based self-assembling drugs for localized drug delivery |
| title | Nucleoside based self-assembling drugs for localized drug delivery |
| title_full | Nucleoside based self-assembling drugs for localized drug delivery |
| title_fullStr | Nucleoside based self-assembling drugs for localized drug delivery |
| title_full_unstemmed | Nucleoside based self-assembling drugs for localized drug delivery |
| title_short | Nucleoside based self-assembling drugs for localized drug delivery |
| title_sort | nucleoside based self-assembling drugs for localized drug delivery |
| topic | drug delivery ; gels ; gemcitabine ; lamivudine ; nucleosides |
| url | https://eprints.nottingham.ac.uk/51547/ https://eprints.nottingham.ac.uk/51547/ https://eprints.nottingham.ac.uk/51547/ |