Opsonic phagocytosis in chronic obstructive pulmonary disease is enhanced by Nrf2 agonists

Opsonic phagocytosis in chronic obstructive pulmonary disease is enhanced by Nrf2 agonists

Rationale: Previous studies have identified defects in bacterial phagocytosis by alveolar macrophages (AM) in patients with chronic obstructive pulmonary disease (COPD) but the mechanisms and clinical consequences remain incompletely defined. Objectives: To examine the effect of COPD on AM phagocyt...

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Main Authors: Bewley, Martin A., Budd, Richard C., Ryan, Eilise, Cole, Joby, Collini, Paul, Marshall, Jennifer, Kolsum, Umme, Beech, Gussie, Emes, Richard D., Tcherniaeva, Irina, Berbers, Gguy A.M., Walmsley, Sarah R., Donaldson, Gavin, Wedzicha, Jadwiga A., Kilty, Iain, Rumsey, William, Sanchez, Yolanda, Brightling, Christopher E., Donnelly, Louise E., Barnes, Ppeter J., Singh, Dave, Whyte, Moira K.B., Dockrell, David H.
Format: Article
Language:English
Published: American Thoracic Society 2018
Subjects:
COPD ; Macrophage ; Phagocytosis ; Anti-oxidant ; Nrf2
Online Access:https://eprints.nottingham.ac.uk/51277/

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