Switchable synthesis of Z-homoallylic boronates and E-allylic boronates by enantioselective copper-catalyzed 1,6-boration
The enantioselective Cu-catalyzed 1,6-boration of (E,E) α,β,γ,δ-unsaturated ketones is described, which gives homoallylic boronates with high enantiomeric purity and unexpectedly high Zselectivity. By changing the solvent, the outcome can be altered to give E-allylic boronates.
| Main Authors: | , , , , , |
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| Format: | Article |
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Wiley
2018
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| Online Access: | https://eprints.nottingham.ac.uk/51268/ |
| _version_ | 1848798455707729920 |
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| author | Luo, Yunfei Wales, Steven M. Korkis, Stamatis E. Roy, Iain D. Lewis, William Lam, Hon Wai |
| author_facet | Luo, Yunfei Wales, Steven M. Korkis, Stamatis E. Roy, Iain D. Lewis, William Lam, Hon Wai |
| author_sort | Luo, Yunfei |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | The enantioselective Cu-catalyzed 1,6-boration of (E,E) α,β,γ,δ-unsaturated ketones is described, which gives homoallylic boronates with high enantiomeric purity and unexpectedly high Zselectivity. By changing the solvent, the outcome can be altered to give E-allylic boronates. |
| first_indexed | 2025-11-14T20:20:03Z |
| format | Article |
| id | nottingham-51268 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T20:20:03Z |
| publishDate | 2018 |
| publisher | Wiley |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-512682020-05-04T19:40:35Z https://eprints.nottingham.ac.uk/51268/ Switchable synthesis of Z-homoallylic boronates and E-allylic boronates by enantioselective copper-catalyzed 1,6-boration Luo, Yunfei Wales, Steven M. Korkis, Stamatis E. Roy, Iain D. Lewis, William Lam, Hon Wai The enantioselective Cu-catalyzed 1,6-boration of (E,E) α,β,γ,δ-unsaturated ketones is described, which gives homoallylic boronates with high enantiomeric purity and unexpectedly high Zselectivity. By changing the solvent, the outcome can be altered to give E-allylic boronates. Wiley 2018-06-12 Article PeerReviewed Luo, Yunfei, Wales, Steven M., Korkis, Stamatis E., Roy, Iain D., Lewis, William and Lam, Hon Wai (2018) Switchable synthesis of Z-homoallylic boronates and E-allylic boronates by enantioselective copper-catalyzed 1,6-boration. Chemistry - a European Journal, 24 (33). pp. 8315-8319. ISSN 1521-3765 1 6-addition; asymmetric catalysis; boron; copper; enantioselectivity https://onlinelibrary.wiley.com/doi/abs/10.1002/chem.201801804 doi:10.1002/chem.201801804 doi:10.1002/chem.201801804 |
| spellingShingle | 1 6-addition; asymmetric catalysis; boron; copper; enantioselectivity Luo, Yunfei Wales, Steven M. Korkis, Stamatis E. Roy, Iain D. Lewis, William Lam, Hon Wai Switchable synthesis of Z-homoallylic boronates and E-allylic boronates by enantioselective copper-catalyzed 1,6-boration |
| title | Switchable synthesis of Z-homoallylic boronates and E-allylic
boronates by enantioselective copper-catalyzed 1,6-boration |
| title_full | Switchable synthesis of Z-homoallylic boronates and E-allylic
boronates by enantioselective copper-catalyzed 1,6-boration |
| title_fullStr | Switchable synthesis of Z-homoallylic boronates and E-allylic
boronates by enantioselective copper-catalyzed 1,6-boration |
| title_full_unstemmed | Switchable synthesis of Z-homoallylic boronates and E-allylic
boronates by enantioselective copper-catalyzed 1,6-boration |
| title_short | Switchable synthesis of Z-homoallylic boronates and E-allylic
boronates by enantioselective copper-catalyzed 1,6-boration |
| title_sort | switchable synthesis of z-homoallylic boronates and e-allylic
boronates by enantioselective copper-catalyzed 1,6-boration |
| topic | 1 6-addition; asymmetric catalysis; boron; copper; enantioselectivity |
| url | https://eprints.nottingham.ac.uk/51268/ https://eprints.nottingham.ac.uk/51268/ https://eprints.nottingham.ac.uk/51268/ |