Human alpha defensin CNV haplotype diversity

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Human alpha defensin CNV haplotype diversity

Humans have highly variable number of alpha defensin genes, with between 3-16 diploid copies. Alpha-defensin genes have important roles in human innate immunity and diseases. Recently, GWAS studies reported this locus associated with IgA nephropathy and periodontitis. However, the underlying mechani...

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Bibliographic Details
Main Author:	Xu, Xiao
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2018
Online Access:	https://eprints.nottingham.ac.uk/51262/

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