Quantitative methods to monitor RNA biomarkers in myotonic dystrophy

Quantitative methods to monitor RNA biomarkers in myotonic dystrophy

Myotonic dystrophy type 1 (DM1) and type 2 (DM2) are human neuromuscular disorders associated with mutations of simple repetitive sequences in afected genes. The abnormal expansion of CTG repeats in the 3′-UTR of the DMPK gene elicits DM1, whereas elongated CCTG repeats in intron 1 of ZNF9/CNBP trig...

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Bibliographic Details
Main Authors: Wojciechowska, Marzena, Sobczak, Krzysztof, Kozlowski, Piotr, Sedehizadeh, Saam, Wojtkowiak-Szlachcic, Agnieszka, Czubak, Karol, Markus, Robert, Lusakowska, Anna, Kaminska, Anna, Brook, J. David
Format: Article
Language:English
Published: Nature Publishing Group 2018
Online Access:https://eprints.nottingham.ac.uk/51160/

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