Three-dimensional spatio-temporal modelling of store operated Ca2+ entry: insights into ER refilling and the spatial signature of Ca2+ signals

QR Code

Three-dimensional spatio-temporal modelling of store operated Ca2+ entry: insights into ER refilling and the spatial signature of Ca2+ signals

The spatial organisation of Orai channels and SERCA pumps within ER-PM junctions is important for enhancing the versatility and specificity of subcellular Ca2+ signals generated during store operated Ca2+ entry (SOCE). In this paper we present a novel three dimensional spatio-temporal model describi...

Full description

Bibliographic Details
Main Authors:	McIvor, Emma, Coombes, Stephen, Thul, Ruediger
Format:	Article
Published:	Elsevier 2018
Subjects:	Calcium signalling; ER-PM junctions; Mathematical modelling; Spatial Ca2+ signature; Orai channels; ER refilling
Online Access:	https://eprints.nottingham.ac.uk/51146/

Similar Items

Comparison of digital elevation models over Australia and external validation using ERS-1 satellite radar altimetry
by: Featherstone, Will, et al.
Published: (2003)

Modelling store operated calcium entry: creating a three dimensional spatio-temporal model to predict local calcium signals
by: McIvor, Emma
Published: (2018)

ER and EER data mapping approaches for integrating petroleum exploration and production business data entities for effective data mining
by: Nimmagadda, Shastri, et al.
Published: (2005)

The biological heterogeneity of oestrogen receptor positive breast cancer and its phenotypic characterisation
by: Habashy, Hany Onsy Fouad Ibrahim
Published: (2011)

Fundamental properties of Ca²⁺ signals
by: Thurley, Kevin, et al.
Published: (2011)

Pre-Rodinia supercontinent Nuna shaping up: A global synthesis with new paleomagnetic results from North China
by: Zhang, S., et al.
Published: (2012)

Oscillations in a point models of the intracellular Ca2+ concentration
by: Thul, Ruediger
Published: (2014)

Multimodal assessment of estrogen receptor mRNA profiles to quantify estrogen pathway activity in breast tumors
by: Muthukaruppan, Anita, et al.
Published: (2017)

Effect of sodium 4-phenylbutyrate on clenbuterol-mediated muscle growth
by: Brown, David M., et al.
Published: (2018)

Microscopic evidence for liquid-liquid separation in supersaturated CaCO3 solutions
by: Wallace, A., et al.
Published: (2013)

Indirect model predictive control strategy with active damping implementation for a direct matrix converter operating at fixed switching frequency
by: Rivera, Marco, et al.
Published: (2017)

Indirect model predictive control strategies with input filter resonance mitigation for a matrix converter operating at fixed switching frequency
by: Rivera, Marco, et al.
Published: (2017)

Statistical modelling of Ca2+ oscillations in the presence of single cell heterogeneity
by: Powell, Jake
Published: (2022)

Un nuevo cálato inscrito de Ca n’Oliver (Cerdanyola del Vallès, Barcelona)
by: Moncunill Martí, Noemí, et al.
Published: (2017)

A bidomain threshold model of propagating calcium waves
by: Thul, Ruediger, et al.
Published: (2008)

Sex differences in endothelial function in porcine coronary arteries: a role for H2O2and gap junctions?
by: Wong, P.S., et al.
Published: (2014)

Long-term peatland condition assessment via surface motion monitoring using the ISBAS DInSAR technique over the Flow Country, Scotland
by: Alshammari, Lubna, et al.
Published: (2018)

Roles of multidimensionality and granularity in warehousing Australian resources data
by: Rudra, Amit, et al.
Published: (2005)

Release currents of IP₃ receptor channel clusters and concentration profiles
by: Thul, Ruediger, et al.
Published: (2004)

Experimental measurements of water molecule binding energies for the second and third solvation shells of [Ca(H₂O)n]2+ complexes
by: Bruzzi, E., et al.
Published: (2017)

Improvement of a convertible undeniable partially blind signature scheme
by: Han, Song, et al.
Published: (2006)

Frequency of elemental events of intracellular Ca²⁺ dynamics
by: Thul, Ruediger, et al.
Published: (2006)

Warehousing of object oriented petroleum data for knowledge mapping
by: Nimmagadda, Shastri, et al.
Published: (2005)

Redox regulation of the calcium activated and voltage gated potassium channel, BK: shaping the pancreatic beta cells action potential and calcium influx
by: Curry, Liam
Published: (2019)

Synthesis and characterization of Fe2O3/CaO derived from Anadara Granosa for methyl ester production
by: Mahmudah, S. Ezzah, et al.
Published: (2016)

Sensitisation waves in a bidomain fire-diffuse-fire model of intracellular Ca²⁺ dynamics
by: Thul, Ruediger, et al.
Published: (2009)

Immunohistochemical evidence of P2X7R, P2X4R and CaMKK2 in pyramidal neurons of frontal cortex does not align with Alzheimer's disease
by: Gaff, Jessica, et al.
Published: (2021)

Towards a predictive model of Ca²⁺ puffs
by: Thul, Ruediger, et al.
Published: (2009)

The relationship between in-vitro endothelial permeability and molecules of the intercellular junction
by: Budworth, Rachel Ann
Published: (2003)

Cannabinoid-mediated short-term plasticity in hippocampus
by: Zachariou, Margarita, et al.
Published: (2014)

Influence of Ca doping and addition of nano-particles of Si and SiC on critical transition temperature of YBa₂Cu₃O₇-8 superconductor
by: Wan Shaaidi, Wan Nurul Ain
Published: (2012)

Integrated collaborative building design using Internet technology
by: Roshani, D.M.R.
Published: (2005)

Significant contribution of organically-bound Mg, Ca, and Fe to inorganic PM10 emission during the combustion of pulverized Victorian brown coal
by: Gao, Xiangpeng, et al.
Published: (2014)

Committal deniable signatures over elliptic curves
by: Han, Song, et al.
Published: (2004)

Investigation into the effect of atmospheric particulate matter (PM2.5 and PM10) concentrations on GPS signals
by: Lau, Lawrence, et al.
Published: (2017)

On the phase space structure of IP3 induced Ca2+ signalling and concepts for predictive modeling
by: Falcke, Martin, et al.
Published: (2018)

Mechanical and durability properties of high volume fly ash (HVFA) concrete containing calcium carbonate (CaCO3) nanoparticles
by: Shaikh, Faiz, et al.
Published: (2014)

Unifying principles of calcium wave propagation: insights from a three-dimensional model for atrial myocytes
by: Thul, Ruediger, et al.
Published: (2015)

Simulated air dives induce superoxide, nitric oxide, peroxynitrite, and Ca2+ alterations in endothelial cells
by: Wang, Q., et al.
Published: (2020)

An efficient algorithm for exact computation of system and survival signatures using binary decision diagrams
by: Reed, Sean
Published: (2017)