Results from the tranexamic acid for primary intracerebral haemorrhage-2 (TICH-2) trial
Background: Haematoma expansion leads to worse outcome in intracerebral haemorrhage (ICH). Tranexamic acid (TXA) is a promising haemostatic agent to prevent haematoma expansion and improve outcome after ICH. Methods: TICH-2 is a multicentre prospective double blind randomised controlled trial, whic...
| Main Authors: | Sprigg, Nikola, Flaherty, Katie, Law, Zhe Kang, Appleton, Jason P., Scutt, Polly, Krishnan, Kailash, Bath, Philip M. |
|---|---|
| Format: | Conference or Workshop Item |
| Published: |
2018
|
| Online Access: | https://eprints.nottingham.ac.uk/51139/ |
Similar Items
TICH-2 Trial – Tranexamic Acid for Intracerebral Haemorrhage 2
by: Sprigg, Nikola, et al.
Published: (2017)
by: Sprigg, Nikola, et al.
Published: (2017)
Statistical analysis plan for the ‘Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage’ (TICH-2) trial
by: Flaherty, Katie, et al.
Published: (2017)
by: Flaherty, Katie, et al.
Published: (2017)
Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial
by: Sprigg, Nikola, et al.
Published: (2018)
by: Sprigg, Nikola, et al.
Published: (2018)
Treatment of spontaneous intracerebral haemorrhage with tranexamic acid
by: Law, Zhe Kang
Published: (2019)
by: Law, Zhe Kang
Published: (2019)
Management of acute intracerebral haemorrhage – an update
by: Law, Zhe Kang, et al.
Published: (2017)
by: Law, Zhe Kang, et al.
Published: (2017)
Prevention of haematoma progression by tranexamic acid in intracerebral haemorrhage patients with and without spot sign on admission scan: a statistical analysis plan of a pre-specified sub-study of the TICH-2 trial
by: Ovesen, Christian, et al.
Published: (2018)
by: Ovesen, Christian, et al.
Published: (2018)
Recruitment challenges in MRI studies of acute intracerebral haemorrhage: experience from the TICH-2 MRI substudy
by: Pszczolkowski, Stefan, et al.
Published: (2018)
by: Pszczolkowski, Stefan, et al.
Published: (2018)
Does tranexamic acid lead to changes in MRI-measures of brain tissue health in patients with spontaneous intracerebral haemorrhage? An MRI sub-study nested within the double-blind randomised controlled TICH-2 trial
by: Dineen, Robert A., et al.
Published: (2018)
by: Dineen, Robert A., et al.
Published: (2018)
Treatment of intracerebral haemorrhage with tranexamic acid: a review of current evidence and ongoing trials
by: Law, Zhe Kang, et al.
Published: (2016)
by: Law, Zhe Kang, et al.
Published: (2016)
Haemostatic therapies for acute spontaneous intracerebral haemorrhage
by: Al-Shahi Salman, Rustam, et al.
Published: (2018)
by: Al-Shahi Salman, Rustam, et al.
Published: (2018)
Outcomes after acute intracerebral haemorrhage
by: Krishnan, Kailash
Published: (2017)
by: Krishnan, Kailash
Published: (2017)
Tranexamic acid for spontaneous intracerebral hemorrhage:
a randomized controlled pilot trial (ISRCTN50867461)
by: Sprigg, Nikola, et al.
Published: (2014)
by: Sprigg, Nikola, et al.
Published: (2014)
Intravenous tranexamic acid for hyperacute primary intracerebral hemorrhage: protocol for a randomized, placebo-controlled trial
by: Sprigg, Nikola, et al.
Published: (2016)
by: Sprigg, Nikola, et al.
Published: (2016)
The effectiveness and safety of antifibrinolytics in patients with acute intracranial haemorrhage: statistical analysis plan for an individual patient data meta-analysis
by: Ker, Katherine, et al.
Published: (2018)
by: Ker, Katherine, et al.
Published: (2018)
Hypercholesterolaemia and vascular dementia
by: Appleton, Jason P., et al.
Published: (2017)
by: Appleton, Jason P., et al.
Published: (2017)
Prediction of major bleeding with a S2TOP-BLEED score in acute ischaemic stroke or TIA patients: a sub-study of the TARDIS trial
by: Woodhouse, Lisa J., et al.
Published: (2018)
by: Woodhouse, Lisa J., et al.
Published: (2018)
Relationship between race and outcome in Asian, Black and Caucasian patients with spontaneous intracerebral haemorrhage: data from the Virtual International Stroke Trials Archive (VISTA) and Efficacy of Nitric Oxide in Stroke trial (ENOS)
by: Krishnan, Kailash, et al.
Published: (2018)
by: Krishnan, Kailash, et al.
Published: (2018)
Blood pressure in acute stroke: to treat or not to treat - that is still the question
by: Bath, Philip M.W., et al.
Published: (2018)
by: Bath, Philip M.W., et al.
Published: (2018)
The prognostic value of the CT scan in primary intracerebral haemorrhage
by: Rathor, Mohammad Yousuf, et al.
Published: (2011)
by: Rathor, Mohammad Yousuf, et al.
Published: (2011)
The prognostic value of the CT scan in Primary Intracerebral Haemorrhage
by: Rathor, Mohammad Yousuf, et al.
Published: (2012)
by: Rathor, Mohammad Yousuf, et al.
Published: (2012)
Role of high augmentation index in spontaneous intracerebral haemorrhage
by: Awang, Mohamed Saufi, et al.
Published: (2010)
by: Awang, Mohamed Saufi, et al.
Published: (2010)
Sonography assisted clot evacuation in
early intracerebral haemorrhage
by: Gene, Teo Eu
Published: (2020)
by: Gene, Teo Eu
Published: (2020)
Platelet and haemoglobin levels in patients on isosorbide mononitrate and/or cilostazol with lacunar ischaemic stroke: data from the LACI-1 trial
by: Appleton, Jason P., et al.
Published: (2018)
by: Appleton, Jason P., et al.
Published: (2018)
Predictors of in-hospital mortality in primary intracerebral haemorrhage in rural Malaysia
by: Rathor, Mohammad Yousuf, et al.
Published: (2011)
by: Rathor, Mohammad Yousuf, et al.
Published: (2011)
Characteristics and outcomes of patients with or without a bleeding event: results from the triple antiplatelets for reducing dependency in ischaemic stroke (TARDIS) trial
by: Woodhouse, Lisa J., et al.
Published: (2018)
by: Woodhouse, Lisa J., et al.
Published: (2018)
Peripheral and central haemodynamics in patients on isosorbide mononitrate and/or cilostazol with lacunar ischaemic stroke: data from the LACI-1 trial
by: Appleton, Jason P., et al.
Published: (2018)
by: Appleton, Jason P., et al.
Published: (2018)
Statistical analysis plan for the ‘Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2)’
by: Scutt, Polly, et al.
Published: (2018)
by: Scutt, Polly, et al.
Published: (2018)
Impact of atrial fibrillation diagnosis or carotid enderterectomy requirement on outcome in patients from the triple antiplatelets for reducing dependency after ischaemic stroke (TARDIS) trial
by: Woodhouse, Lisa J., et al.
Published: (2018)
by: Woodhouse, Lisa J., et al.
Published: (2018)
Predictors of in-hospital mortality in primary intracerebral haemorrhage in East coast of Peninsular Malaysia
by: Rathor, Mohammad Yousuf, et al.
Published: (2012)
by: Rathor, Mohammad Yousuf, et al.
Published: (2012)
Evaluation of intracerebral haemorrhages surface area using artificial intelligence in computed tomography
by: Huddin, Azzam Basseri, et al.
Published: (2022)
by: Huddin, Azzam Basseri, et al.
Published: (2022)
The REstart or STop Antithrombotics Randomised Trial (RESTART) after stroke due to intracerebral haemorrhage: study protocol for a randomised controlled trial
by: Al-Shahi Salman, Rustam, et al.
Published: (2018)
by: Al-Shahi Salman, Rustam, et al.
Published: (2018)
Consent procedures and relationship with outcome in the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2)
by: Scutt, Polly, et al.
Published: (2018)
by: Scutt, Polly, et al.
Published: (2018)
The use of early, mild hypothermia in
the treatment of stable,
spontaneous, supra tentorial,
intracerebral
haemorrhage
by: Andrean, Rusin
Published: (2009)
by: Andrean, Rusin
Published: (2009)
The Insulin Resistance Intervention after Stroke trial: a perspective on future practice and research
by: Bath, Philip M.W., et al.
Published: (2016)
by: Bath, Philip M.W., et al.
Published: (2016)
Blood pressure management in acute stroke
by: Appleton, Jason P., et al.
Published: (2016)
by: Appleton, Jason P., et al.
Published: (2016)
Therapeutic potential of transdermal glyceryl trinitrate in the management of acute stroke
by: Appleton, Jason P., et al.
Published: (2016)
by: Appleton, Jason P., et al.
Published: (2016)
Bolus administration of tranexamic acid with a maintenance dose via infusion and strict blood pressure control for non-traumatic intracerebral hemorrhages
by: Arumugam, Ananda
Published: (2014)
by: Arumugam, Ananda
Published: (2014)
Nitric oxide donors (nitrates), L-arginine, or nitric oxide synthase inhibitors for acute stroke
by: Bath, Philip M.W., et al.
Published: (2017)
by: Bath, Philip M.W., et al.
Published: (2017)
Interim analysis of ambulance logistics and timings in patients recruited into the Rapid intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2)
by: Dixon, Mark, et al.
Published: (2018)
by: Dixon, Mark, et al.
Published: (2018)
Inflammatory biomarkers and its value in predicting survival and outcome among patients with spontaneous intracerebral haemorrhage
by: A/L Rajapathyk, Senthil Kumar
Published: (2015)
by: A/L Rajapathyk, Senthil Kumar
Published: (2015)
Similar Items
-
TICH-2 Trial – Tranexamic Acid for Intracerebral Haemorrhage 2
by: Sprigg, Nikola, et al.
Published: (2017) -
Statistical analysis plan for the ‘Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage’ (TICH-2) trial
by: Flaherty, Katie, et al.
Published: (2017) -
Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial
by: Sprigg, Nikola, et al.
Published: (2018) -
Treatment of spontaneous intracerebral haemorrhage with tranexamic acid
by: Law, Zhe Kang
Published: (2019) -
Management of acute intracerebral haemorrhage – an update
by: Law, Zhe Kang, et al.
Published: (2017)