The impact of a computerised test of attention and activity (QbTest) on diagnostic decision-making in children and young people with suspected ADHD: single-blind randomised controlled trial

Background: Diagnosis of attention deficit hyperactivity disorder (ADHD) relies on subjective methods which can lead to diagnostic uncertainty and delay. This trial evaluated the impact of providing a computerised test of attention and activity (QbTest) report on the speed and accuracy of diagnostic...

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Main Authors: Hollis, Chris, Hall, Charlotte L., Guo, Boliang, James, Marilyn, Boadu, Janet, Groom, Madeleine J., Brown, Nikki, Kaylor-Hughes, Catherine, Moldavsky, Maria, Valentine, Althea Z., Walker, Gemma M., Daley, David, Sayal, Kapil, Morriss, Richard
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Published: Wiley 2018
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Online Access:https://eprints.nottingham.ac.uk/51036/
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author Hollis, Chris
Hall, Charlotte L.
Guo, Boliang
James, Marilyn
Boadu, Janet
Groom, Madeleine J.
Brown, Nikki
Kaylor-Hughes, Catherine
Moldavsky, Maria
Valentine, Althea Z.
Walker, Gemma M.
Daley, David
Sayal, Kapil
Morriss, Richard
author_facet Hollis, Chris
Hall, Charlotte L.
Guo, Boliang
James, Marilyn
Boadu, Janet
Groom, Madeleine J.
Brown, Nikki
Kaylor-Hughes, Catherine
Moldavsky, Maria
Valentine, Althea Z.
Walker, Gemma M.
Daley, David
Sayal, Kapil
Morriss, Richard
author_sort Hollis, Chris
building Nottingham Research Data Repository
collection Online Access
description Background: Diagnosis of attention deficit hyperactivity disorder (ADHD) relies on subjective methods which can lead to diagnostic uncertainty and delay. This trial evaluated the impact of providing a computerised test of attention and activity (QbTest) report on the speed and accuracy of diagnostic decision making in children with suspected ADHD. Methods: Randomised, parallel, single-blind controlled trial in mental health and community paediatric clinics in England. Participants were 6-17 years-old and referred for ADHD diagnostic assessment; all underwent assessment-as-usual, plus QbTest. Participants and their clinician were randomised to either receive the QbTest report immediately (QbOpen group) or the report was withheld (QbBlind group). The primary outcome was number of consultations until a diagnostic decision confirming/excluding ADHD within six-months from baseline. Health economic cost-effectiveness and cost utility analysis was conducted. Assessing QbTest Utility in ADHD: A Randomised Controlled Trial was registered at ClinicalTrials.gov (https://clinicaltrials.gov/ct2/show/NCT02209116). Results: One hundred and thirty two participants were randomised to QbOpen group (123 analysed) and 135 to QbBlind group (127 analysed). Clinicians with access to the QbTest report (QbOpen) were more likely to reach a diagnostic decision about ADHD (Hazard Ratio 1.44, 95% CI 1.04 to 2.01). At six-months, 76% of those with a QbTest report had received a diagnostic decision, compared with 50% without. QbTest reduced appointment length by 15% (Time Ratio 0.85, 95% CI 0.77 to 0.93), increased clinicians’ confidence in their diagnostic decisions (Odds Ratio 1.77, 95% CI 1.09 to 2.89) and doubled the likelihood of excluding ADHD. There was no difference in diagnostic accuracy. Health economic analysis showed a position of strict dominance, however cost savings were small suggesting that the impact of providing the QbTest report within this trial can best be viewed as ‘cost neutral’. Conclusion: QbTest may increase the efficiency of ADHD assessment pathway allowing greater patient throughput with clinicians reaching diagnostic decisions faster without compromising diagnostic accuracy.
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spelling nottingham-510362020-05-04T19:33:38Z https://eprints.nottingham.ac.uk/51036/ The impact of a computerised test of attention and activity (QbTest) on diagnostic decision-making in children and young people with suspected ADHD: single-blind randomised controlled trial Hollis, Chris Hall, Charlotte L. Guo, Boliang James, Marilyn Boadu, Janet Groom, Madeleine J. Brown, Nikki Kaylor-Hughes, Catherine Moldavsky, Maria Valentine, Althea Z. Walker, Gemma M. Daley, David Sayal, Kapil Morriss, Richard Background: Diagnosis of attention deficit hyperactivity disorder (ADHD) relies on subjective methods which can lead to diagnostic uncertainty and delay. This trial evaluated the impact of providing a computerised test of attention and activity (QbTest) report on the speed and accuracy of diagnostic decision making in children with suspected ADHD. Methods: Randomised, parallel, single-blind controlled trial in mental health and community paediatric clinics in England. Participants were 6-17 years-old and referred for ADHD diagnostic assessment; all underwent assessment-as-usual, plus QbTest. Participants and their clinician were randomised to either receive the QbTest report immediately (QbOpen group) or the report was withheld (QbBlind group). The primary outcome was number of consultations until a diagnostic decision confirming/excluding ADHD within six-months from baseline. Health economic cost-effectiveness and cost utility analysis was conducted. Assessing QbTest Utility in ADHD: A Randomised Controlled Trial was registered at ClinicalTrials.gov (https://clinicaltrials.gov/ct2/show/NCT02209116). Results: One hundred and thirty two participants were randomised to QbOpen group (123 analysed) and 135 to QbBlind group (127 analysed). Clinicians with access to the QbTest report (QbOpen) were more likely to reach a diagnostic decision about ADHD (Hazard Ratio 1.44, 95% CI 1.04 to 2.01). At six-months, 76% of those with a QbTest report had received a diagnostic decision, compared with 50% without. QbTest reduced appointment length by 15% (Time Ratio 0.85, 95% CI 0.77 to 0.93), increased clinicians’ confidence in their diagnostic decisions (Odds Ratio 1.77, 95% CI 1.09 to 2.89) and doubled the likelihood of excluding ADHD. There was no difference in diagnostic accuracy. Health economic analysis showed a position of strict dominance, however cost savings were small suggesting that the impact of providing the QbTest report within this trial can best be viewed as ‘cost neutral’. Conclusion: QbTest may increase the efficiency of ADHD assessment pathway allowing greater patient throughput with clinicians reaching diagnostic decisions faster without compromising diagnostic accuracy. Wiley 2018-04-26 Article PeerReviewed Hollis, Chris, Hall, Charlotte L., Guo, Boliang, James, Marilyn, Boadu, Janet, Groom, Madeleine J., Brown, Nikki, Kaylor-Hughes, Catherine, Moldavsky, Maria, Valentine, Althea Z., Walker, Gemma M., Daley, David, Sayal, Kapil and Morriss, Richard (2018) The impact of a computerised test of attention and activity (QbTest) on diagnostic decision-making in children and young people with suspected ADHD: single-blind randomised controlled trial. Journal of Child Psychology and Psychiatry . ISSN 1469-7610 QbTest Attention deficit hyperactivity disorder ADHD assessment continuous performance test https://onlinelibrary.wiley.com/doi/abs/10.1111/jcpp.12921 doi:10.1111/jcpp.12921 doi:10.1111/jcpp.12921
spellingShingle QbTest
Attention deficit hyperactivity disorder
ADHD
assessment
continuous performance test
Hollis, Chris
Hall, Charlotte L.
Guo, Boliang
James, Marilyn
Boadu, Janet
Groom, Madeleine J.
Brown, Nikki
Kaylor-Hughes, Catherine
Moldavsky, Maria
Valentine, Althea Z.
Walker, Gemma M.
Daley, David
Sayal, Kapil
Morriss, Richard
The impact of a computerised test of attention and activity (QbTest) on diagnostic decision-making in children and young people with suspected ADHD: single-blind randomised controlled trial
title The impact of a computerised test of attention and activity (QbTest) on diagnostic decision-making in children and young people with suspected ADHD: single-blind randomised controlled trial
title_full The impact of a computerised test of attention and activity (QbTest) on diagnostic decision-making in children and young people with suspected ADHD: single-blind randomised controlled trial
title_fullStr The impact of a computerised test of attention and activity (QbTest) on diagnostic decision-making in children and young people with suspected ADHD: single-blind randomised controlled trial
title_full_unstemmed The impact of a computerised test of attention and activity (QbTest) on diagnostic decision-making in children and young people with suspected ADHD: single-blind randomised controlled trial
title_short The impact of a computerised test of attention and activity (QbTest) on diagnostic decision-making in children and young people with suspected ADHD: single-blind randomised controlled trial
title_sort impact of a computerised test of attention and activity (qbtest) on diagnostic decision-making in children and young people with suspected adhd: single-blind randomised controlled trial
topic QbTest
Attention deficit hyperactivity disorder
ADHD
assessment
continuous performance test
url https://eprints.nottingham.ac.uk/51036/
https://eprints.nottingham.ac.uk/51036/
https://eprints.nottingham.ac.uk/51036/